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CALCIUM THIOGLYCOLATE

SYNONYMS:
Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective; calcium 2-sulfidoacetate;C2H2CaO2S;130.18 g/mol;Molecular Weight;37457-75-3;calcium 2-sulfidoacetate;Thioglycolic Acid; calcium 2-sulfidoacetate;C2H2CaO2S;130.18 g/mol;calcium 2-sulfidoacetate;colorless liquid;Ammonium Thioglycolate;
calcium 2-sulfidoacetate;C2H2CaO2S;130.18 g/mol;Molecular Weight;37457-75-3;calcium 2-sulfidoacetate;Thioglycolic Acid; organic compound;carboxylic acid;colorless liquid;Ammonium Thioglycolate; Butyl Thioglycolate; Calcium Thioglycolate; Ethanolamine Thioglycolate; Glyceryl Thioglycolate; Isooctyl Thioglycolate; Isopropyl Thioglycolate; Magnesium Thioglycolate; Methyl Thioglycolate; Potassium Thioglycolate; Sodium Thioglycolate;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective;
C2H2CaO2S;130.18 g/mol;Molecular Weight;37457-75-3;calcium 2-sulfidoacetate;Thioglycolic Acid; organic compound;carboxylic acid;colorless liquid;Ammonium Thioglycolate; Butyl Thioglycolate; Calcium Thioglycolate; Ethanolamine Thioglycolate; Glyceryl Thioglycolate; Isooctyl Thioglycolate; Isopropyl Thioglycolate; Magnesium Thioglycolate; Methyl Thioglycolate; Potassium Thioglycolate; Sodium Thioglycolate;Calcium thioglycolate trihydrate;calcium;thioglycolate;trihydrate;Calcium thioglycolate trihydrate;alcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;
Molecular Weight;37457-75-3;calcium 2-sulfidoacetate;Thioglycolic Acid; organic compound;carboxylic acid;colorless liquid;Ammonium Thioglycolate; Butyl Thioglycolate; Calcium Thioglycolate; Ethanolamine Thioglycolate; Glyceryl Thioglycolate; Isooctyl Thioglycolate; Isopropyl Thioglycolate; Magnesium Thioglycolate; Methyl Thioglycolate; Potassium Thioglycolate; Sodium Thioglycolate;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective;Calcium; Thioglycolate;Calcium Thioglycolate; Calcium Thioglycolate Trihydrate;Thioglycolate Trihydrate;Trihydrate;fine crystalline powder;Mercaptoacetic acid calcium salt;depilatory agent;potassium thioglycolate;kalsiyum;less soluble;less effective; crystalline powder;
organic compound;carboxylic acid;colorless liquid;Ammonium Thioglycolate; Butyl Thioglycolate; Calcium Thioglycolate; Ethanolamine Thioglycolate; Glyceryl Thioglycolate; Isooctyl Thioglycolate; Isopropyl Thioglycolate; Magnesium Thioglycolate; Methyl Thioglycolate; Potassium Thioglycolate; Sodium Thioglycolate;Calcium thioglycolate trihydrate;calcium;thioglycolate;trihydrate;Calcium thioglycolate trihydrate;

 


Calcium Thioglycolate Trihydrate is a fine crystalline powder of calcium thioglycolate (Mercaptoacetic acid calcium salt) that is used as a depilatory agent.
Calcium thioglycolate is less soluble and also less effective in comparison to potassium thioglycolate. On the other hand the irritancy is much lower.


Chemical Names:
Calcium thioglycolate (1:1)

Property Name Property Value
Molecular Weight 130.18 g/mol
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 0
Exact Mass 129.940141 g/mol
Monoisotopic Mass 129.940141 g/mol
Topological Polar Surface Area 41.1 A^2
Heavy Atom Count 6
Formal Charge 0
Complexity 46.8
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes


Data gaps
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product Cosmetic Ingredient Review Assessments
258 studies in PubMed science library may include information on the toxicity of this chemical see search results -> NLM PubMed

Ecotoxicology
Concern Reference
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)
Concern Reference
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List

Persistence and bioaccumulation
Concern Reference
Not suspected to be persistent Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List


What Is It?
Thioglycolic Acid is an organic compound that contains a thiol group (-SH) and carboxylic acid. It is a colorless liquid. Thioglycolic Acid and some salts and esters of Thioglycolic Acid, such as Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate and Sodium Thioglycolate are used in hair coloring products, permanent wave products, hair straightening products and depilatory products.

Why is it used in cosmetics and personal care products?
Thioglycolic Acid and it salts and esters modify hair fibers to facilitate changes to the structure of the fibers, such as with permanent waves or with hair straightening. They are also used to chemically break down hair fibers so that unwanted hair can be removed by simply wiping it from the skin.

Scientific Facts:
Thioglycolic Acid and its salts and esters break disufide bonds in the cortex of the hair. After washing, the hair is treated with a mild solution of hydrogen peroxide, which causes new bonds to form, giving hair the rigid structure necessary for permanent waves.

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