1-9 A-D E-G H-M N-P Q-S T-Z

ERİTORBİK ASİT ( ERYTHORBIC ACID)

ERYTHORBIC ACID

Synonyms: Erythorbic Acid; Eritorbik Asit; Erythorbicacid; Erythrobic acid; Erythorbic; Acid; Eritrobik asit; Eritrobikasit; Eritorbic asit; Eriytorbik asit; D-(-)-Isoascorbic acid;izo askorbik asit, izoaskorbik asit, Izoaskorbikasit; Izoaskorbik asit; Iso askorbik asit; Izo askorbik asit; Izo askorbikasit; izoaskorbikasit,isoaskorbik asit, iso askorbik asit, isoaskorbik asit; D-erythro-Hex-2-enoic acid ?-lactone; Erythroascorbic acid; D-(-)-Isoascorbic acid D-Araboascorbic acid; Erythorbic acid; Glucosaccharonic acid; NSC 8117; Araboascorbic acid; D-; Isoascorbic Acid; Erythorbic acid; 89-65-6; D-Araboascorbic acid; Araboascorbic acid; D-Erythorbic acid; Isovitamin C; Neo-cebicure; Saccharosonic acid; Mercate 5; Glucosaccharonic acid; Erythroascorbic acid, D-; D-(-)-Isoascorbic acid; FEMA Number: 2410; 2,3-Didehydro-D-erythro-hexono-1,4-lactone; D-ASCORBIC ACID, ISO; Erycorbin; FEMA No. 2410; CCRIS 6568; HSDB 584; UNII-311332OII1; D-erythro-Hex-2-enonic acid, gamma-lactone; NSC 8117; D-erythro-3-Oxohexonic acid lactone; EINECS 201-928-0; D-erythro-3-Ketohexonic acid lactone; MFCD00005378; (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one; (R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one; 3-Oxohexonic acid lactone, D-erythro-; BRN 0084271; D-erythro-hex-2-enonic acid gamma-lactone; 3-Keto-D-erythro-hexonic acid gamma-lactone; CHEBI:51438; CIWBSHSKHKDKBQ-DUZGATOHSA-N; D-erythro-hex-2-enono-1,4-lactone; 311332OII1; E315; D-Erythro-hex-2-enonic acid, gamma-lactone,; D(-)-Isoascorbic acid, 98%; D-erythro-Hex-2-enonic acid, .gamma.-lactone; erythroascorbic acid; Erythorbic acid [NF]; Erythorbatd; D-Isoascorbicacid ercate5;NSC 8117;FEMA 2410;ERYCORBIN;D-(-mercate"5";)-Isoascor;NEOCEBICURE;ERYTHORBATE;ISOVITAMIN C; D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid, Glucosaccharonic acid, NSC 8117 Araboascorbic acid; d-Araboascorbic acid; D-2,3-didehydro-erythro-hexono-1,4-lactone; E315; Erycorbin; Erythorbic acid; d-Erythorbic acid; d-Erythro-ascorbic acid D-Erythro-hex-2-enoic acid; D-erythro-Hex-2-enonic acid, .gamma.-lactone; D-Erythro-3-ketohexonic acid lactone; D-Erythro-3-oxohexonic acid lactone; FEMA Number: 2410 Glucosaccharonic acid; Isoascorbic acid; D-Isoascorbic acid; Isovitamin C; gamma-Lactone; Mercate 5; Neo-cebicure; Saccharosonic acid; D-araboascorbic acid; erythorbic acid erythroascorbic acid; isoascorbic acid; isoascorbic acid, disodium salt; isoascorbic acid, monosodium salt; isoascorbic acid, sodium salt; sodium erythorbate; Erythorbic acid Isoascorbic acid; D-Isoascorbic acid; 89-65-6; D-Araboascorbic acid; Araboascorbic acid; D-Erythorbic acid; Isovitamin C; Neo-cebicure; Saccharosonic acid; Mercate 5 Glucosaccharonic acid; Erythroascorbic acid; D-(-)-Isoascorbic acid; FEMA Number: 2410; 2,3-Didehydro-D-erythro-hexono-1,4-lactone; D-ASCORBIC ACID, ISO; Erycorbin; FEMA No. 2410 CCRIS 6568; HSDB 584; UNII-311332OII1; D-erythro-Hex-2-enonic acid, gamma-lactone; NSC 8117; D-erythro-3-Oxohexonic acid lactone; EINECS 201-928-0; D-erythro-3-Ketohexonic acid lactone MFCD00005378; (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one; (R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one; 3-Oxohexonic acid lactone, D-erythro- BRN 0084271; D-erythro-hex-2-enonic acid gamma-lactone; 3-Keto-D-erythro-hexonic acid gamma-lactone; Hex-2-enonic acid gamma-lactone, D-erythro-; CHEBI:51438; CIWBSHSKHKDKBQ-DUZGATOHSA-N D-erythro-hex-2-enono-1,4-lactone; 311332OII1; E315; D-Erythro-hex-2-enonic acid, gamma-lactone,; D(-)-Isoascorbic acid, 98%; D-erythro-Hex-2-enonic acid, .gamma.-lactone erythroascorbic acid; Erythorbic acid [NF]; Erythorbatd; D-Isoascorbicacid; 1f9g; AC1L1NQG; DSSTox_CID_6537; D-(-)-Araboascorbic acid; EC 201-928-0; DSSTox_RID_78143 DSSTox_GSID_26537; SCHEMBL18678; 5-18-05-00026 (Beilstein Handbook Reference); CHEMBL486293; SCHEMBL3700961; DTXSID6026537; D-(-)-Isoascorbic acid, 98%; KS-00000UH8 Tox21_201111; SBB017515; AKOS015856346; ZINC100006772; ZINC100057602; LS-2352; RL05634; CAS-89-65-6; D-erythro-Hex-2-enonic acid, g-lactone; NCGC00258663-01; D-erythro-Hex-2-enoic acid gamma-lactone D-Isoascorbic acid, >=99%, FCC, FG; O272; A0520; FT-0624450; C20364; J-506944; (2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one; 7179C406-7CCF 4C07-9125-AA71E28FB983 (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one; (5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-hydrofuran-2-one; Erythorbic acid, United States Pharmacopeia (USP) Reference Standard (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one; D-Isoascorbic acid(Erythorbic acid) CAS 89-65-6; Erythorbic acid or erythorbate, formerly known Other name: D-erythro-Hexonicacid, 3-keto-, g-lactone(6CI);Erythorbic acid (7CI);Araboascorbic acid; Araboascorbic acid, D-;D-(-)-Isoascorbic acid;D-Araboascorbic acid; D-Erythorbic acid;D-Isoascorbicacid;D-arabino-Ascorbic acid;Glucosaccharonic acid;Isoascorbic acid;Isovitamin C;Saccharosonic acid

 

 

Functions and Applications
1.Erythorbic acid is produced in acidic condition by sodium erythorbate. 
2.Erythorbic acid has strong reducing action and has effects on reducing blood press, diuresis,generationg liver glycogen,excreting pigment,detoxifying the body. 
3.It is non-toxic.Its other applications are familiar to sodium erythorbate. Sodium erythorbateand erythorbic acid are generally recognized as the lastest A-class 
Green products internationally and have become the commodities in short supply both at home and abroad
Erythorbic acid
United States Pharmacopeia (USP) Reference Standard
Synonym: D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid, Glucosaccharonic acid, NSC 8117 CAS Number 89-65-6 
Empirical Formula (Hill Notation) C6H8O6 Molecular Weight 176.12 Beilstein Registry Number 84271 MDL number MFCD00005378 PubChem Substance ID 329749380
Erythorbic acid United States Pharmacopeia (USP) Reference Standard SDS Similar Products SKU-Pack Size Availability Price (EUR) 1241823-50MG Estimated to ship on 
14.08.19 407.00 To order products, please contact your local dealer. Click here Product Recommendations W241008 D-Isoascorbic acid FCC, FG 856061 D-(-)-
Isoascorbic acid 98% 496332 Sodium D-isoascorbate monohydrate 97% top Purchase Safety & Documentation Properties Related Categories Analytical Standards, 
Erythorbate, Isoascorbic acid. Identifiers CAS Number 89-65-6 ? 3D model (JSmol) Interactive image ChEBI CHEBI:51438 ? ChemSpider 16736142 ? ECHA InfoCard 100.001.753
E number E315 (antioxidants, ...) PubChem CID 6981 UNII 311332OII1 ? CompTox Dashboard (EPA) DTXSID6026537 Edit this at Wikidata InChI
verify (what is ?? ?) Infobox references Erythorbic acid (isoascorbic acid, D-araboascorbic acid) is a stereoisomer of ascorbic acid (vitamin C).[1] It is synthesized by a reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose or by strains of Penicillium that have been selected for this feature.[2] It is denoted by E number E315, and is widely used as an antioxidant in processed foods.[3]
/OTHER TOXICITY INFORMATION/ At the last evaluation an /Acceptable Daily Intake/ (ADI) of 0-5 mg/kg bw was allocated based on a long-term study in the rat. The present /Joint FAO/WHO Expert Committee on Food Additives/ reviewed new toxicological studies on isoascorbic acid and its sodium salt, and metabolic and nutritional studies of the interactions with ascorbic acid. 
The reduced form of erythorbic acid was incorporated into human erythrocytes at the rate of 20% per 2 hours and the rate of uptake of this form was proportional to the extracellular concentration. The oxidized form of erythorbic acid, D-dehydroisoascorbic acid, became incorporated more rapidly than the reduced form, at a rate of 50% per 5 minutes, and 80% of the acid absorbed was subsequently reduced within the cells. The reduced form of erythorbic acid was more stable in plasma than the oxidized form, of which 61% was degraded in 60 minutes. In erythrocytes, the reduced form was stable, as in plasma, and the oxidized form slightly less so.
[Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).] **PEER REVIEWED**

 

 

 

Erythorbic acid apparently was not reabsorbed after glomerular filtration, and, therefore, was excreted from the kidneys more rapidly than L-ascorbic acid.
[Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).] **PEER REVIEWED**

 

 

 

Male F344 rats (five per group, 6-week-old) were given 5% sodium erythorbate in feed for 22 weeks. The rats eliminated totals of 203.3 +/- 33.2 mg/100 mL erythorbic acid and 9.0 +/- 5.1 mg/100 mL dehydroerythorbic acid during the study. Ascorbic acid and dehydroascorbic acid were not detected. Urine pH was 6.98 +/- 0.31, which was significantly different from that of rats given basal diet alone (6.31 +/- 0.18; p <0.05). Urine osmolarity also differed significantly from controls; osmolarity was 1378 +/- 277 mOsmol/kg H20 in rats given sodium erythorbate and 1756 +/- 200 mOsmol/kg H20 in rats of the control group. Crystals were detected in urine of rats given basal diet and sodium erythorbate or basal diet alone. /Sodium erythorbate/
[Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).] **PEER REVIEWED**

 

 

 


Biological Half-Life: 
In dogs, this resulted in a half-life of approximately 30 minutes for erythorbic acid in the plasma.
[Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).] **PEER REVIEWED**
Interactions: 
The modifying effects of 3 antioxidants, sodium L-ascorbate (SA), ascorbic acid (AA) and sodium erythorbate (SE) on two-stage gastric carcinogenesis in F344 rats initiated with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) were investigated. Administration of 5% SE in the diet significantly decreased the incidence of dysplasia of the pylorus and, more marginally the incidence of papilloma of the forestomach, whereas administration of 5% and 1% SA and 5% AA in the diet was not associated with effect. These results suggest that SE exerts a weak inhibitory effect on gastric carcinogenesis. /Sodium erythorbate/
[Shirai T et al; Cancer Lett 29 (3): 283-8 (1985)] **PEER REVIEWED**
The marked azotemia & other evidence of renal damage induced in rats & dogs by rapid iv admin of tetracycline-HCl (50 mg/kg) was prevented by concomitant admin of ascorbic acid (125 mg/kg or more). D-isoascorbic acid had a similar effect when tested in rats.
[POLEC ET AL; J PHARMACOL EXP THER 178 (1): 152 (1971)] **PEER REVIEWED** PubMed Abstract
Pharmacology:
Therapeutic Uses: 
Erythorbic acid is a stereoisomer of l-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of l-ascorbic acid.
[Rowe, R.C., Sheskey, P.J., Quinn, M.E.; (Eds.), Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press, London, England 2009, p. 250] **PEER REVIEWED** 
Interactions: 
The modifying effects of 3 antioxidants, sodium L-ascorbate (SA), ascorbic acid (AA) and sodium erythorbate (SE) on two-stage gastric carcinogenesis in F344 rats initiated with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) were investigated. Administration of 5% SE in the diet significantly decreased the incidence of dysplasia of the pylorus and, more marginally the incidence of papilloma of the forestomach, whereas administration of 5% and 1% SA and 5% AA in the diet was not associated with effect. These results suggest that SE exerts a weak inhibitory effect on gastric carcinogenesis. /Sodium erythorbate/
[Shirai T et al; Cancer Lett 29 (3): 283-8 (1985)] **PEER REVIEWED**
The marked azotemia & other evidence of renal damage induced in rats & dogs by rapid iv admin of tetracycline-HCl (50 mg/kg) was prevented by concomitant admin of ascorbic acid (125 mg/kg or more). D-isoascorbic acid had a similar effect when tested in rats.
[POLEC ET AL; J PHARMACOL EXP THER 178 (1): 152 (1971)] **PEER REVIEWED** PubMed Abstract 
Erythorbic acid PubChem CID: 54675810 Structure: Erythorbic acid_small.png Erythorbic acid_3D_Structure.png Find Similar Structures Chemical Safety: Irritant
Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula: C6H8O6 Chemical Names: Erythorbic acid Isoascorbic acid
D-Isoascorbic acid 89-65-6 D-Araboascorbic acid More... Molecular Weight: 176.12 g/mol Dates: Modify: 2019-07-13 Create: 2011-12-26 D-isoascorbic acid is an ascorbic acid.
from ChEBI 1Structures HelpNew Window 1.12D Structure HelpNew Window Find Similar Structures Get Image Download Chemical Structure Depiction Erythorbic acid.png
Full screen Zoom in Zoom out 1.23D Conformer HelpNew Window Get Image Download Interactive Chemical Structure Model Ball and Stick Sticks Wire-Frame Space-Filling
Show Hydrogens Animate Full screen Zoom in Zoom out from PubChem 2Names and Identifiers HelpNew Window 2.1Computed Descriptors HelpNew Window
2.1.1IUPAC Name HelpNew Window (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one from PubChem
2.1.2InChI HelpNew Window InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5-/m1/s1 from PubChem 2.1.3InChI Key HelpNew Window
CIWBSHSKHKDKBQ-DUZGATOHSA-N from PubChem 2.1.4Canonical SMILES HelpNew Window C(C(C1C(=C(C(=O)O1)O)O)O)O from PubChem 2.1.5Isomeric SMILES HelpNew Window
C([C@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O from PubChem 2.2Molecular Formula HelpNew Window C6H8O6 from EU Food Improvement Agents; PubChem 2.3Other Identifiers
2.3.1CAS HelpNew Window 89-65-6 from ChemIDplus; EPA Chemicals under the TSCA; EPA DSSTox; European Chemicals Agency (ECHA) Related CAS 146-75-8 (di-hydrochloride salt)
6381-77-7 (mono-hydrochloride salt) 7378-23-6 (hydrochloride salt) from ChemIDplus Other CAS 74242-57-2 98966-42-8 from ChemIDplus 2.3.2EC Number 201-928-0 from EU Food Improvement Agents; European Chemicals Agency (ECHA)
2.3.3FEMA Number HelpNew Window 2410 from Flavor and Extract Manufacturers Association (FEMA) 2.3.4UNII HelpNew Window 311332OII1 
from FDA/SPL Indexing Dat 2.3.5Wikipedia HelpNew Window Erythorbic acid from Wikipedia 2.4Synonyms COMPOUND SUMMARY Erythorbic acid PubChem CID: 54675810 Structure: 
Erythorbic acid_small.png Erythorbic acid_3D_Structure.png Find Similar Structures Chemical Safety: Irritant
Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula: C6H8O6 Chemical Names: Erythorbic acid Isoascorbic acid D-Isoascorbic acid 89-65-6
D-Araboascorbic acid More... Molecular Weight: 176.12 g/mol Dates: Modify: 2019-07-13 Create: 2011-12-26 D-isoascorbic acid is an ascorbic acid. from ChEBI
1Structures HelpNew Window 1.12D Structure HelpNew Window Find Similar Structures Get Image Download Chemical Structure Depiction Erythorbic acid.png
Full screen Zoom in Zoom out from PubChem 1.23D Conformer HelpNew Window Get Image Download Interactive Chemical Structure Model Ball and Stick Sticks Wire-Frame
Space-Filling Show Hydrogens Animate Full screen Zoom in Zoom out from PubChem 2Names and Identifiers HelpNew Window 2.1Computed Descriptors HelpNew Window
2.1.1IUPAC Name HelpNew Window (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one from PubChem 2.1.2InChI HelpNew Window InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5-/m1/s1 from PubChem
2.1.3InChI Key HelpNew Window CIWBSHSKHKDKBQ-DUZGATOHSA-N from PubChem 2.1.4Canonical SMILES HelpNew Window C(C(C1C(=C(C(=O)O1)O)O)O)O from PubChem
2.1.5Isomeric SMILES HelpNew Window C([C@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O from PubChem 2.2Molecular Formula HelpNew Window C6H8O6 from EU Food Improvement Agents; PubChem
2.3Other Identifiers HelpNew Window 2.3.1CAS HelpNew Window 89-65-6 from ChemIDplus; EPA Chemicals under the TSCA; EPA DSSTox; European Chemicals Agency (ECHA)
Related CAS 146-75-8 (di-hydrochloride salt) 6381-77-7 (mono-hydrochloride salt) 7378-23-6 (hydrochloride salt) from ChemIDplus Other CAS 74242-57-2 98966-42-8 from ChemIDplus
2.3.2EC Number HelpNew Window 201-928-0 from EU Food Improvement Agents; European Chemicals Agency (ECHA) 2.3.3FEMA Number HelpNew Window 2410 from Flavor and Extract Manufacturers Association (FEMA)
2.3.4UNII HelpNew Window 311332OII1 from FDA/SPL Indexing Data 2.3.5Wikipedia HelpNew Window Erythorbic acid from Wikipedia 2.4Synonyms HelpNew Window
2.4.1MeSH Entry Terms HelpNew Window D-araboascorbic acid erythorbic acid erythroascorbic acid isoascorbic acid isoascorbic acid, disodium salt isoascorbic acid, monosodium salt isoascorbic acid, sodium salt
sodium erythorbate from MeS 2.4.2Depositor-Supplied Synonyms HelpNew Window Erythorbic acid Isoascorbic acid D-Isoascorbic acid 89-65-6 D-Araboascorbic acid Araboascorbic acid
D-Erythorbic acid Isovitamin C Neo-cebicure Saccharosonic acid Mercate 5 Glucosaccharonic acid Erythroascorbic acid, D- D-(-)-Isoascorbic acid FEMA Number: 2410 2,3-Didehydro-D-erythro-hexono-1,4-lactone
D-ASCORBIC ACID, ISO Erycorbin FEMA No. 2410 CCRIS 6568 HSDB 584 UNII-311332OII1 D-erythro-Hex-2-enonic acid, gamma-lactone NSC 8117 D-erythro-3-Oxohexonic acid lactone EINECS 201-928-0
D-erythro-3-Ketohexonic acid lactone MFCD00005378 (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
3-Oxohexonic acid lactone, D-erythro- BRN 0084271 D-erythro-hex-2-enonic acid gamma-lactone 3-Keto-D-erythro-hexonic acid gamma-lactone Hex-2-enonic acid gamma-lactone, D-erythro-
CHEBI:51438 CIWBSHSKHKDKBQ-DUZGATOHSA-N D-erythro-hex-2-enono-1,4-lactone 311332OII1 E315 D-Erythro-hex-2-enonic acid, gamma-lactone, D(-)-Isoascorbic acid, 98% D-erythro-Hex-2-enonic acid, .gamma.-lactone
erythroascorbic acid Erythorbic acid [NF] Erythorbatd D-Isoascorbicacid 1f9g AC1L1NQG DSSTox_CID_6537 D-(-)-Araboascorbic acid EC 201-928-0 DSSTox_RID_78143 DSSTox_GSID_26537
SCHEMBL18678 5-18-05-00026 (Beilstein Handbook Reference) CHEMBL486293 SCHEMBL3700961 DTXSID6026537 D-(-)-Isoascorbic acid, 98% KS-00000UH8 Tox21_201111 SBB017515 AKOS015856346 ZINC100006772
ZINC100057602 LS-2352 RL05634 CAS-89-65-6 D-erythro-Hex-2-enonic acid, g-lactone NCGC00258663-01 D-erythro-Hex-2-enoic acid gamma-lactone D-Isoascorbic acid, >=99%, FCC, FG O272
A0520 FT-0624450 C20364 J-506944 (2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one 7179C406-7CCF-4C07-9125-AA71E28FB983 (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
(5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-hydrofuran-2-one Erythorbic acid, United States Pharmacopeia (USP) Reference Standard (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one 
3Chemical and Physical Properties HelpNew Window 3.1Computed Properties HelpNew Window Property Name Property Value Molecular Weight 176.12 g/mol XLogP3 -1.6
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 2 Exact Mass 176.032088 g/mol Monoisotopic Mass 176.032088 g/mol
Topological Polar Surface Area 107 A^2 Heavy Atom Count 12 Formal Charge 0 Complexity 232 Isotope Atom Count 0 Defined Atom Stereocenter Count 2
8.2FDA Substances Added to Food HelpNew Window Substance ERYTHORBIC ACID Used for (Technical Effect) FLAVORING AGENT OR ADJUVANT Document Number (21 CFR) 175.105
182.3041 from FDA Center for Food Safety and Applied Nutrition (CFSAN) 8.3Food Additive Status HelpNew Window FDA Food Additive Status Erythorbic acid - PRES, GRAS/FS, X-ref - Isoascorbic acid
from FDA Center for Food Safety and Applied Nutrition (CFSAN) FDA Food Additive Status 8.4Evaluations of the Joint FAO/WHO Expert Committee on Food Additives - JECFA HelpNew Window
Chemical Name D-ARABOASCORBIC ACID ADI NOT SPECIFIED Evaluation Year 1990 Report TRS 806-JECFA 37/9 FAO/WHO Food Additive Evaluations (JECFA)
9Pharmacology and Biochemistry HelpNew Window 9.1MeSH Pharmacological Classification HelpNew Window Antioxidants Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)
from MeSH 9.2Absorption, Distribution and Excretion New Window Erythorbic acid is readily absorbed and metabolized. Following an oral dose of 500 mg of erythorbic acid to human subjects the blood level curves for ascorbic acid and erythorbic acid showed a similar rise. In five human subjects, an oral dose of 300 mg was shown to have no effect on urinary excretion of ascorbic acid.
from HSDB The reduced form of erythorbic acid was incorporated into human erythrocytes at the rate of 20% per 2 hours and the rate of uptake of this form was proportional to the extracellular concentration. The oxidized form of erythorbic acid, D-dehydroisoascorbic acid, became incorporated more rapidly than the reduced form, at a rate of 50% per 5 minutes, and 80% of the acid absorbed was subsequently reduced within the cells. The reduced form of erythorbic acid was more stable in plasma than the oxidized form, of which 61% was degraded in 60 minutes. In erythrocytes, the reduced form was stable, as in plasma, and the oxidized form slightly less so.
Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).
from HSDB Erythorbic acid apparently was not reabsorbed after glomerular filtration, and, therefore, was excreted from the kidneys more rapidly than L-ascorbic acid.
Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).
from HSDB Male F344 rats (five per group, 6-week-old) were given 5% sodium erythorbate in feed for 22 weeks. The rats eliminated totals of 203.3 +/- 33.2 mg/100 mL erythorbic acid and 9.0 +/- 5.1 mg/100 mL dehydroerythorbic acid during the study. Ascorbic acid and dehydroascorbic acid were not detected. Urine pH was 6.98 +/- 0.31, which was significantly different from that of rats given basal diet alone (6.31 +/- 0.18; p <0.05). Urine osmolarity also differed significantly from controls; osmolarity was 1378 +/- 277 mOsmol/kg H20 in rats given sodium erythorbate and 1756 +/- 200 mOsmol/kg H20 in rats of the control group. Crystals were detected in urine of rats given basal diet and sodium erythorbate or basal diet alone. /Sodium erythorbate/
Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).
from HSDB 9.3Biological Half-Life HelpNew Window In dogs, this resulted in a half-life of approximately 30 minutes for erythorbic acid in the plasma.
Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate; International Journal of Toxicology 18 ( Suppl 3): 1-26 (1999).
from HSDB 10Use and Manufacturing HelpNew Window 10.1Use Classification HelpNew Window JECFA Functional Classes Food Additives: ANTIOXIDANT from FAO/WHO Food Additive Evaluations (JECFA)
10.2Household Products HelpNew Window NLM Household Products and Categories Revlon Colorist Expert Color and Glaze System, Medium Ash Blonde 81 [Personal care]
Revlon Colorist Expert Color and Glaze System, Light Golden Brown 63 [Personal care] Revlon Colorist Expert Color and Glaze System, Light Brown 60 [Personal care]
... see the complete list of household products from NLM Household Products Database 10.3Uses HelpNew Window EPA CPDat Chemical and Product Categories 37 items View More
Download Erythorbic acid United States Pharmacopeia (USP) Reference Standard Synonym: D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid, Glucosaccharonic acid, NSC 8117
CAS Number 89-65-6 Empirical Formula (Hill Notation) C6H8O6 Molecular Weight 176.12 Beilstein Registry Number 84271 MDL number MFCD00005378 PubChem Substance ID 329749380
Erythorbic acid United States Pharmacopeia (USP) Reference Standard SDS Similar Products SKU-Pack Size Availability Price (EUR) 1241823-50MG Estimated to ship on 14.08.19
407.00 To order products, please contact your local dealer. Click her Product Recommendations W241008 D-Isoascorbic acid FCC, FG 856061 D-(-)-Isoascorbic acid 98% 496332
Sodium D-isoascorbate monohydrate 97% top Purchase Safety & Documentation Properties Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards E - F More...
Scorbutic (low collagen) granulomas were induced by s.c.
injection of carrageenan to vitamin C-deficient male guinea pigs. 
Isoascorbic acid and ascorbic acid (6 doses of 100 mg i.p. at 12 h
intervals) were similarly effective in restoring collagen synthesis
in the granuloma although the concentration of erythorbic acid 12 h
after injection was lower than that of ascorbic acid 24 h after
injection (Robertson, 1963).

 

(b) in vitro studies

 

 

Ascorbic acid and erythorbic acid demonstrated similar activity
in promoting the hydroxylation of peptidyl proline in a cell-free
system (Hutton et al., 1967; Kutnink et al., 1969) and these
observations have been confirmed using a purified prolyl 4-
dihydroxylase preparation (Kurata et al., 1987).

Erythorbic acid had a similar effect to ascorbic acid in
protecting hepatic microsomal UDP-glucuronyltransferase activity
towards p-aminophenol against excess substrate but no protection was
afforded by ascorbate-2-sulfate or alpha-tocopherol (Neumann &
Zannoni, 1988).

The effects of ascorbate and erythorbate on collagen synthesis
were studied in cultured human skin fibroblasts. At concentrations
of 0.25 mM in the culture medium both ascorbate and erythorbate
increased collagen synthesis about eightfold with no significant
change in synthesis of non-collagen protein. Lysyl hydroxylase
activity increased 3-fold in response to ascorbate or erythorbate
administration. After prolonged exposure of cells to ascorbate or
erythorbate, prolyl hydroxylase activity was decreased to a similar
extent. The results were taken to indicate that collagen
polypeptide synthesis, posttranslational hydroxylations and
activities of the two hydroxylases are independently regulated by
ascorbate, with erythorbate having similar effects at the high
concentrations used (Murad et al., 1981).
In further studies using human skin fibroblasts, ascorbate
stimulated the rate of incorporation of labelled proline into total
collagenase-sensitive protein without changing the specific activity
of intracellular free proline. The effect of ascorbate was maximal
at a concentration of 30 µM and resulted in a four-fold increase of
incorporation. Erythorbate also stimulated collagen synthesis but
at considerably higher concentrations of 250-300 µM. The
stimulation of collagen synthesis by ascorbate and erythorbate was
accompanied by a decline in prolyl hydroxylase activity and a rise
in lysyl hydroxylase activity; again ascorbate was the more
effective (Murad et al., 1983).
The protective effects of ascorbic and erythorbic acid against
carbon tetrachloride-induced lipid peroxidation were investigated in
guinea pigs using exhalation of pentane and ethane as an index of
in vivo lipid peroxidation. It was observed that equal doses (750
mg/kg b.w., i.p.) of ascorbic acid or isoascorbic acid provided the
same degree of protection for a period of at least 4 hours (Kunert &
Tappel, 1983). The authors concluded that the antioxidant function
of ascorbic acid is relatively non-specific and that the two
stereoisomers do not differ with regard to their antioxidant
properties in vivo.
2.3 Observations in humans

 

 

In order to determine whether erythorbic acid could displace
ascorbic acid from the tissue, urinary levels of ascorbic acid were
measured after ingestion of 300 mg erythorbic acid by 5 healthy
human volunteers who had been previously repleted by administration
of 500 mg ascorbic acid for 7 days. Urinary analyses indicated that
ascorbic acid excretion was not affected by treatment with
erythorbic acid and that there was no significant displacement of
ascorbic acid from tissues (Kadin & Osadca, 1959).
The influence of erythorbic acid on ascorbic acid metabolism
and status was investigated in 11 healthy, non-pregnant women
volunteers. The volunteers were maintained in a metabolic unit and
fed a formula diet devoid of vitamin C for 54 days. After depletion
of 24 days, the subjects received increasing supplements of ascorbic
acid (30 mg/d, 60 mg/d and 90 mg/d for successive periods of 10
days) in the presence or absence of 600 mg/d of erythorbic acid. 
The depletion resulted in a marked decrease in ascorbic acid in all
blood indices and during the study some subjects developed signs of
scurvy. Ascorbic acid supplements of 30 mg/d for 10 days failed to
increase plasma ascorbate concentrations; 60 mg for 10 days caused a
small increase and 90 mg/d resulted in a mean ascorbic acid
concentration of 29 mmol/l. Erythorbic acid did not cause any
adverse effects but rather had a small ascorbic acid-sparing effect
(Sauberlich et al., 1989).
3. COMMENTS

 

 

At the last evaluation an ADI of 0-5 mg/kg b.w. was allocated
based on a long-term study in the rat. The present Committee
reviewed new toxicological studies on isoascorbic acid and its
sodium salt, and metabolic and nutritional studies of the
interactions with ascorbic acid.
HORNIG, D. & WEISER, H. (1976). Interaction of erythorbic acid with
ascorbic acid catabolism. Internat. J. Vit. Nutr. Res., 46, 40-
47.
HUGHES, R.E. & HURLEY, R.J. (1969). The uptake of D-araboascorbic
acid (D-isoascorbic acid) by guinea-pig tissues. Br. J. Nutr., 
23, 211-216.
HUGHES, R.E., HURLEY, R.J. & JONES, P.R. (1971). Vitamin C activity
of D-araboascorbic acid. Nutr. Rep. Internal., 4, 177-183.
HUGHES, R.E. & JONES, P.R. (1970). D-Araboascorbic acid and guinea-
pig scurvy. Nutr. Rep. Internat., 1, 275-279.
HUTTON, J.J., TAPPEL, A.L. & UDENFRIEND, S. (1967). Cofactor and
substrate requirements of collagen proline hydroxylase. Arch.
Biochem. Biophys., 118, 231-240.
HWANG, U.K. & CONNORS, N.A. (1974). Investigation of the toxic and
teratogenic effects of GRAS substances to the developing chicken
embryo. Report submitted to the U.S. Food and Drug Administration,
28th February, 1974.
IIOKA, H., MORIYAMA, I., KYUMA, M., AKASAKI, M., KATOH, Y., ITOH,
K., HINO, K., OKAMURA, Y., NINOMIYA, Y., KIYOZUKA, Y, ITANI, Y. &
ICHIJO, M. (1987). The study of placental L-ascorbate (Vitamin C)
transport mechanism (using microvillus membrane vesicles). Acta
Obst. Gyneac. Jpn., 39, 837-841.
IKEUCHI, M. (1955). Biochemical studies on D-araboascorbic acid in
vitamin C deficiency. J. Vitaminol., 1, 193-199.
INAI, K. AKAMIZU, H., ETO, R., NISHIDA, T., OHE, K., KOBUKE, T.,
NAMBU, S., MATSUKI, K. & TOKUOKA, S. (1989). Tumorigenicity study
of sodium erythorbate administered orally to mice. Hiroshima J.
Med. Sci., 38, 135-139.
ISHIDATE, M., SOFUNI, T., YOSHIKAWA, K., HAYASHI, M., NOHMI,T.,
SAWADA, M. & MATSUOKA, A. (1984). Primary mutagenicity screening of
food additives currently used in Japan. Fd. Chem. Toxicol., 22,
623-636.
ITO, N. FUKUSHIMA, S. & HIROSE, M. (1987). Modification of the
carcinogenic response by antioxidants. In: Toxicological aspects of
food (K. Miller, ed.). pp. 253-293. Elsevier Applied Science:
London & New York.
ITO, N., HIROSE, M. FUKUSHIMA, S., TSUDA, H., SHIRAI, T. &
TATEMATSU, M. (1986a). Studies on antioxidants: their carcinogenic
and modifying effects on chemical carcinogenesis. Fd. Chem.
Toxicol., 24, 1071-1082.
ITO, N., HIROSE, M., FUKUSHIMA, S., TSUDA, H., TATEMATSU, M. &
ASAMOTO, M. (1986b). Modifying effects of antioxidants on chemical
carcinogenesis. Toxic. Pathol., 14, 315-323.
KADIN, H. OSADCA, M. (1959). Biochemistry of erythorbic acid. 
Human blood levels and urinary excretion of ascorbic and erythorbic
acids. J. Agric. Food Chem., 7, 358-360.
KALLNER, A., HARTMANN, D. & HORNIG, D. (1977). On the absorption of
ascorbic acid in man. Internat. J. Vit. Nutr. Res., 47, 383-388.
KAWANASHI, T., OHNO, Y., SUNOUCHI, M., ONODA, K., TAKAHASHI, A.,
KASUYA, Y. & OMORI, Y. (1981). Studies on nitrosamine formation by
the interaction between drugs and nitrite II. Hepatotoxicity by
simultaneous administration of several drugs and nitrite. J. Tox.
Sci., 6, 271-286.
KHATAMI, M., STRAMM, L.E. & ROCKEY, J.H. (1986). Ascorbate
transport in cultured cat retinal pigment epithelial cells. Exp.
Eye Res., 43, 607-615.
KÜBLER, W. & GEHLER, J. (1970). Zur Kinetik der enteralen
Ascorbinsaure-Resorption. Ein Beitrag zur Berechnung nicht
dosisproportionaler Resorptionvergänge. Internat. Z. Vit. Forshung,
40, 442-453.
KUNERT, K.J. & TAPPEL, A.L. (1983). The effect of vitamin C on in
vivo lipid peroxidation in guinea pigs as measured by pentane and
ethane production. Lipids, 18, 271-274.
KURATA, T., YU, R. & ARAKAWA, N. (1987). Some aspects of the role
of ascorbic acid in proline hydroxylation. Agric. Biol. Chem., 
51, 2299-2301.
KUTNINK, M.A., TOLBERT, B.M., RICHMOND, V.L. & BAKER, E.M. (1969). 
Efficacy of the ascorbic acid stereoisomers in proline hydroxylation
in vitro. Proc. Soc. Exp. Biol. Med., 132, 440-442.
LEE, K., CHINN, B.L., GREGER, J.L., GRAHAM, K.L., SHIMAOKA, J.E., &
LIEBERT, J.C. (1984). Bioavailability of iron to rats from nitrite
and erythorbate cured processed meats. J. Agric. Food Chem., 32,
856-860.
LEE, K. & GREGER, J.L. (1985). Rebuttal to bioavilability of iron
from nitrite and erythorbate cured processed meats. J. Agric. Food
Chem., 33, 320-321.
LEHMAN, A.J., FITZHUGH, O.G., NELSON, A.A. & WOODARD, G. (1951). 
The pharmacological evaluation of antioxidants. Adv. Food Res., 
3, 197-208.
LINNER, E. & NORDSTRÖM, K. (1969). Transfer of D-isoascorbic acid

 

 

and L-ascorbic acid into guinea pig eyes. Doc. Ophthalmol., 26,
164-170.
LITTON BIONETICS INC. (1976). Mutagenic evaluation of compound FDA
71-66, erythorbic acid. Report prepared under DHEW Contract no. FDA
223-74-2104. Kensington, MD.
MAHONEY, A.W. & HENDRICKS, D.G. (1985). Comments on bioavailability

 

 

of iron to rats from nitrite and erythorbate cured processed meats. 
J. Agric. Food Chem., 33, 319.
MATSUOKA, A., HAYASHI, M. & ISHIDATE, M. (1979). Chromosomal

 

 

aberration tests on 29 chemicals combined with S9 mix in vitro. 
Mutat. Res., 66, 277-290.
MELLORS, A.J., NAHRWOLD, D.L., & ROSE, R.C. (1977). Ascorbic acid

 

 

flux across mucosal border of guinea pig and human ileum. Am. J.
Physiol., 233, E374-E379.
MIYATA, Y., FUKUSHIMA, S., HIROSE, M., MASUI, T. & ITO, N. (1985).

 

 

Short-term screening of promoters of bladder carcinogenesis in N-
butyl-N-(4-hydroxybutyl)nitrosamine-initiated, unilaterally ureter-
ligated rats. Jpn. J. Cancer Res. (Gann), 76, 828-834.
MURAD, S. GROVE, D., LINDBERG, K.A., REYNOLDS, G., SIVARAJAH, A. &

 

 

PINNELL, S.R. (1981). Regulation of collagen synthesis by ascorbic
acid. Proc. Natl. Acad. Sci. USA., 78, 2879-2882.
MURAD, S., TAJIMA, S., JOHNSON, G.R., SIVARAJAH, A. & PINNELL, S.R.

 

 

(1983). Collagen synthesis in cultured human skin fibroblasts:
effect of ascorbic acid and its analogs. J. Invest. Dermatol., 
81, 158-162.
NABER, E.C. (1975). Investigations on the toxic and teratogenic

 

 

effects of GRAS substances on the developing chick embryo. Report
of investigations conducted under Contract No. 72-343 for the U.S.
Food and Drug Administration, PHS, DHEW.
NEUMANN, C.M. & ZANNONI, V.G. (1988). Ascorbic acid deficiency and

 

 

hepatic UDP-glucuronyltransferase. Drug Metab. Disp., 16, 551-
556.
NEWELL, G.W., JORGENSON, T.A. & SIMMON, V.F. (1974). Study of the

 

 

mutagenic effects of sodium erythorbate (FDA No. 71-68). Compound
Report No. 4 prepared for U.S. Food and Drug Administration, HEW,
Rockville, Maryland.
PELLETIER, O. (1969a). Differential determination of D-isoascorbic

 

 

acid and L-ascorbic acid in guinea pig organs. Can. J. Biochem., 
47, 449-453.
PELLETIER, O. (1969b). Turnover rates of D-isoascorbic acid and L-

 

 

ascorbic acid in guinea pig organs. Can. J. Physiol. Pharmacol.,
47, 993-997.
PELLETIER, O. & GODIN, C. (1969). Vitamin C activity of D-

 

 

isoascorbic acid for the guinea pig. Can. J. Physiol. Pharmacol.,
47, 985-991.
REIFF, J.S. & FREE, A.H. (1959). Nutritional studies with

 

 

isoascorbic acid in the guinea pig. J. Agric. Food Chem., 7, 55-
56.
RIVERS, J.M., HUANG, E.D., & DODDS, M.L. (1963). Human metabolism

 

 

of l-ascorbic and erythorbic acid. J. Nutr., 81, 163-168.
ROBERTSON, W. VAN B. (1963). D-ascorbic acid and collagen synthesis

 

Biochem. Biophys. Acta., 74, 137-139.

 

 

ROBINSON & UMBREIT (1956). Excretion after oral administration to
fasting dogs. Unpublished report. Submitted to WHO by Pfizer Inc.
ROBINSON, UMBREIT & SILBER, R.H. (1956). Comparison of metabolism

 

 

of ascorbic acid and isoascorbic acid. Unpublished report. 
Submitted to WHO by Pfizer Inc.
SAUBERLICH, H.E., KRETSCH, M.J., TAYLOR, P.C., JOHNSON, H.L. &

 

 

SKALA, J. H. (1989). Ascorbic acid and erythorbic acid metabolism
in nonpregnant women. Am. J. Clin. Nutr., 50, 1039-1049.
SHIRAI, T., MASUDA, A., FUKUSHIMA, S., HOSODA, K. & ITO, N. (1985).

 

 

Effects of sodium L-ascorbate and related compounds on rat stomach
carcinogenesis initiated by N-methyl-N'-nitro-N-nitrosoguanidine. 
Cancer Letts., 29, 283-288.
SILIPRANDI, L., VANNI, P., KESSLER, M. & SEMENZA, G. (1979). Na-

 

 

dependent, electroneutral L-ascorbate transport across brush border
membrane vesicles from guinea pig small intestine. Biochim.
Biophys. Acta., 552, 129-142.
SPECTOR, R. & LORENZO, A.V. (1974) Specificity of the ascorbic acid

 

 

transport system of the central nervous system. Am. J. Physiol.,
226, 1468-1473.
SUZUKI, E., KURATA, T., KODA, M. & ARAKAWA, N. (1987). Erythorbic

 

 

acid content in tissues of guinea pigs administered erythorbic acid. 
J. Nutr. Sci. Vitaminol., 33, 169-175.

 

 

 

SUZUKI, E., KURATA, T., KODA, M. & ARAKAWA, N. (1988). Effects of
graded doses of erythorbic acid on activities of drug metabolic
enzyme and phosphatases in guinea pigs. J. Nutr. Sci. Vitaminol.,
34, 439-447.

 

 

 

SUZUKI, E., KURATA, T. & ARAKAWA, N. (1989). Effect of erythorbic
acid administration on acitivities of drug metabolic enzyme and
phosphatases in guinea pigs administered an adequate amount of
ascorbic acid. J. Nutr. Sci. Vitaminol., 35, 123-131.

 

 

 

SUZUKI, E., KURATA, T., SANCEDA, N. & ARAKAWA, N. (1986). Effect of
graded doses of erythorbic acid on ascorbic acid content of tissues
of guinea pigs. J. Nutr. Sci. Vitaminol., 32, 335-342.

 

 

 

TOGGENBURGER, G., HÄUSERMANN, M., MÜTSCH, B, GENONI, G, KESSLER, M,
WEBER, F, HORNIG, D., O'NEILL, B. & SEMENZA, G. (1981). Na+-
Dependent, potential-sensitive L-ascorbate transport across the
brush border membrane vesicles from kidney cortex. Biochim.
Biophys. Acta, 646, 433-443.

 

 

 

TOGGENBURGER, G., LANDOLDT, M. & SEMENZA, G. (1979). Na-dependent,
electroneutral L-ascorbate transport across brush border membrane
vesicles from human small intestine. FEBS Letts., 108, 473-476.

 

 

 

TSAO, C.S. & SALIMI, S.L. (1983). Influence of erythorbic acid on
ascorbic acid retention and elimination in the mouse. Internat. J.
Vit. Nutr. Res., 53, 258-264.

 

 

 

TURNBULL, J.D., SAUBERLICH, H.E. & OMAYE, S.T. (1979). Effects of
ascorbic acid deficiency and of erythorbic acid on blood components
in the Cynomolgus monkey. Internat. J. Vit. Nutr. Res., 49, 92-
102.

 

 

 

WANG, M.M., FISHER, K.H. & DODDS, M.L. (1962). Comparative
metabolic response to erythorbic acid and ascorbic acid by the
human. J. Nutr., 77, 443-447.

 

 

 

WILLIAMS, R.S. & HUGHES, R.E. (1972). Dietary protein, growth and
retention of ascorbic acid in guinea-pigs. Br. J. Nutr., 28, 167-
172.

 

 

 

WOOLLEY, D.W. & KRAMPITZ, L.O. (1943). Production of a scurvy-like
condition by feeding of a compound structurally related to ascorbic
acid. J. Exp. Med., 78, 333-339.
See Also:
Toxicological Abbreviations
Ürün Adı: Erythorbic Acid BP, EP, FCC

 

Eş anlamlı kelimeler: D-isoascorbic acid, D-Iso askorbik asit

CAS Numarası: 89-65-6

Özellikleri: Beyaz ila hafif sarımsı bir toz.

Saflık (Deneme):% 99.0 -% 101.5

Moleküler Formül: C6H8O6

Yapısı:

Erythorbic Acid, D-isoascorbic Acid FCC BP EP Structure-1.pngErythorbic Acid, D-isoascorbic Acid FCC BP EP Structure formula -2.jpg

Paket: 25Kgs / Ctn; 25kgs /

Paket: 25Kgs / Ctn; 25Kgs / Fiber Drum

Anahtar kelimeler:

Erythorbic Acid BP, EP, FCC;

D-izoaskorbik asit, D-İzo askorbik asit

 

Açıklaması

D-izoaskorbik asit, D-İzo askorbik asit olarak da adlandırılan Erythorbic Acid BP, EP, FCC, bir anti-oksidan olarak kullanılan askorbik asitin optik bir izomeridir.

 

Antioksidan olarak kullanılır. Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-izo askorbik asit), gıda maddelerinin ve oksijenin gıda üzerindeki etkilerini engelleyerek koruyucu madde olarak çalışan gıda katkı maddeleridir ve sağlığa yararlı olabilir. Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit), sadece orijinal gıda rengini ve doğal aromalarını korumakla kalmaz, aynı zamanda herhangi bir yan etkisi olmayan gıdaların raf ömrünü de arttırır.

Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) gıda endüstrisinde önemli bir antioksidandır, gıdaların rengini, doğal lezzetini koruyabilir ve herhangi bir toksik ve yan etki olmadan depolama süresini uzatabilir. Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit), et işleme, meyve, sebze, teneke ve reçel vb. Alanlarda da kullanılır. Ayrıca bira, üzüm şarabı, yumuşak içecek gibi içeceklerde de kullanılır. içecek, meyve çayı ve meyve suyu vb.

 

Erythorbic asit (izoaskorbik asit, D-araboaskorbik asit, (D-) eritroaskorbik asit), askorbik asidin (C vitamini) bir stereoizomeridir. Metil 2-keto-D-glukonat ve sodyum metoksit arasındaki bir reaksiyon ile sentezlenir. Sükroz veya bu özellik için seçilmiş olan Penicillium suşları ile de sentezlenebilir. Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-İzo askorbik asit) E315 E ile gösterilir ve işlenmiş gıdalarda yaygın bir antioksidan olarak kullanılır.

Erithorbik asitin besin değeri yönlerini araştırmak için klinik denemeler yapılmıştır. Böyle bir çalışma, genç kadınlarda erythorbic asitin C vitamini metabolizması üzerindeki etkilerini araştırdı; C vitamini tutulumuna veya vücuttan temizlenmeye hiçbir etkisi bulunmamıştır. Daha sonraki bir araştırma, erithorbik asitin demir olmayan demir emiliminin güçlü bir güçlendiricisi olduğunu bulmuştur.

FDA, taze olarak tüketilmesi öngörülen yiyeceklerde (salata barları gibi) koruyucu olarak sülfit kullanımını yasakladığı için, Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-İzo askorbik asit) gıda koruyucu arttı.

Dahası, kürlenmiş etlerde ve dondurulmuş sebzelerde koruyucu olarak kullanılır.

 

Eskiden izoaskorbik asit ve D-araboaskorbik asit olarak bilinen eritrosit asit veya erithorbat, askorbik asitin bir stereoizomeridir. Sükrozdan üretilen bitkisel türevli bir besin katkısıdır. E Numara E315 ile gösterilir ve işlenmiş gıdalarda yaygın bir antioksidan olarak kullanılır. Erithorbik asitin besin değeri yönlerini araştırmak için klinik denemeler yapılmıştır. Böyle bir çalışma, genç kadınlarda erythorbic asitin C vitamini metabolizması üzerindeki etkilerini araştırdı; C vitamini tutulumuna veya vücuttan temizlenmeye hiçbir etkisi bulunmamıştır.

 

Erythorbic Acid Hakkında

Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) C vitamini bir stereoizomerdir ve bu nedenle C vitamininin kimyasal yapısı benzerdir. Erythorbic Acid beyazdan açık sarı veya kristal toz, kokusuz, asit tadı, erime noktası 166-172 - ve ayrıştırma, Erythorbic Acid yavaş yavaş ışığa maruz kaldığında kararır. Kuru durum, Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) havada oldukça stabildir ve havaya maruz kaldığında ve hızla dejenere olduğunda çözelti içinde, E315 askorbik asitin fizyolojik aktivitesinde neredeyse hiçbir rol oynamaz. , Erythorbic Asit antioksidan özellikleri askorbik asit, ama Erythorbic Acid BP, EP, FCC (D-isoascorbic asit, D-Iso askorbik asit) zayıf ısı direnci, yoğunluğu azaltılmış, ağır metal iyonlarının ayrışması, suda oda içinde çözünebilir teşvik edebilir 40 g / 100 ml, çözünürlüğü etanol içinde çözünür, 5 g / 100 mi, gliserin içinde çözünmez, benzende çözünmez, pH değerinin pH değeri olan% 1'lik sulu çözelti. Antioksidan sodyum eritrozat, C vitamininin antioksidan kapasitesinden çok daha fazladır, rolünü güçlendirmek için C vitamini içermez, ancak Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-İzo askorbik asit), vücut emilimini engellemez ve askorbik asit kullanımı. E315 insan alımı, vücut CUS Gıda ve İlaç İdaresi'ne dönüştürülebilir (1980) Erythorbic Asit genellikle güvenli maddeler olarak kabul edilir.

 

Fengchen Group, Çin'den Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) Tozu'nun önde gelen tedarikçisi konumundadır. Biz toptan ve toplu miktarlarda uzmanlaşmak, tüm müşterilerimize ihtiyaç duyduklarında Erythorbic Acid BP, EP, FCC (D-isoascorbic asit, D-Iso askorbik asit) toz doğru tedarikçisi var sağlamak. Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) Tozu satın alırken veya satın alırken lütfen Fengchen Grubuna dönün.

 

Analiz sertifikası

madde

Özellikleri - FCC IV

isim

 

 

Erythorbic Asit 
(D-izoaskorbik asit, D-İzo askorbik asit)

 

Görünüm

Beyaz kokusuz, kristalin toz veya granüller

Tahlil (kuru bazda)

99.0 -% 100.5

Kimyasal formül

C6H8O6

Özel rotasyon

-16,5 --- -18,0 º

Ateşleme sırasında kalıntı

<% 0.3

Kurutma kaybı

<% 0.4

Parçacık boyutu

40 mesh

Ağır metal

<10 ppm maks

Öncülük etmek

<5 ppm

Arsenik

<3 ppm

 

En Kaliteli, saf Erythorbic Asit BP, EP, FCC (D-isoascorbic asit, D-Iso askorbik asit) Çin'de toz / madde fabrikası; Çin Çin'de Erythorbic Asit BP, EP, FCC (D-isoascorbic asit, D-Iso askorbik asit) Toz Hammadde Tedarikçiler. Çin Çin'de Erythorbic Asit BP, EP, FCC (D-isoascorbic asit, D-Iso askorbik asit) Toz Üreticileri.

 

 

Eğer erythorbic asit, d-isoascorbic asit fcc bp ep için arıyorsanız, bize hoş geldiniz. Biz bu alanda önde gelen ve profesyonel Çin üreticileri ve tedarikçileri bulunmaktadır. Rekabetçi fiyat ve iyi satış sonrası servis mevcuttur.
ilgili ürünler
Chlortetracycline Hidroklorür veya Chlortetracycline HCL CAS 64-72-2
Chlortetracycline Hidroklorür veya Chlortetracycline...

 

 

 

Oxolinic Acid CAS 14698-29-4 ve Sodium Oxolinate Toz Hammaddesi, API CAS 59587-08-5
Oxolinic Acid CAS 14698-29-4 ve Sodium Oxolinate Toz...

 

 

 

Asetil Spiramycin, Spiramycin Adipate, Spiramycin Base
Asetil Spiramycin, Spiramycin Adipate, Spiramycin Base

 

 

 

Vitamin A Palmitat Tozu, A Vitamini Palmitat Yağı Gıda Sınıfı ve Pharma Sınıfı CAS 79-81-2
Vitamin A Palmitat Tozu, A Vitamini Palmitat Yağı Gı...

 

 

 

L-Karnitin Hcl CAS 6645-46-1 DL-Karnitin Hidroklorür CAS 461-05-2
L-Karnitin Hcl CAS 6645-46-1 DL-Karnitin Hidroklorür...

 

 

 

Metformin Hcl veya Metformin Hidroklorür API, Hammadde Tozu CAS 1115-70-4
Metformin Hcl

 

 

 

Erythorbic Acid
Also known as Isoascoribic acid, erythoribic acid is a natural product, vegetable derived food additive produced from sucrose. Erythoribic acid is an important antioxidant in the food industry, which can keep the color, natural flavor of foods and lengthen food storage without toxic and side effects. Erythoribic acid is used in cured meat processing, frozen fruits, frozen vegetables, jams, and in the beverage industry such as beer, grape wine, soft drink, fruit juice and fruit teas. Erythoribic acid's use has increased tremendously ever since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods to be eaten fresh (ie: salad bar ingredients).

 

Packaging: 25 kg Carton

 

 

Erythorbic acid (isoascorbic acid, D-araboascorbic acid) is a stereoisomer of ascorbic acid (vitamin C). It is synthesized by a reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose or by strains of Penicillium that have been selected for this feature. It is denoted by E number E315, and is widely used as an antioxidant in processed foods.Clinical trials have been conducted to investigate aspects of the nutritional value of erythorbic acid. One such trial investigated the effects of erythorbic acid on vitamin C metabolism in young women; no effect on vitamin C uptake or clearance from the body was found. A later study found that erythorbic acid is a potent enhancer of nonheme-iron absorption.Since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods intended to be eaten fresh (such as salad bar ingredients), the use of erythorbic acid as a food preservative has increased. It is also used as a preservative in cured meats and frozen vegetables.It was first synthesized in 1933 by the German chemists Kurt Maurer and Bruno Schiedt.
Erythorbic acid

 

 

 

Erythorbic acid, formerly known as isoascorbic acid and D-araboascorbic acid, is a stereoisomer of ascorbic acid. It is a vegetable-derived food additive produced from sucrose. It is denoted by E number E315, and is widely used as an antioxidant in processed foods. Clinical trials have been conducted to investigate aspects of the nutritional value of erythorbic acid. One such trial investigated the effects of erythorbic acid on vitamin C metabolism in young women; no effect on vitamin C uptake or clearance from the body was found. A later study found that erythorbic acid is a potent enhancer of nonheme-iron absorption. Since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods intended to be eaten fresh, the use of erythorbic acid as a food preservative has increased. It is also used as a preservative in cured meats and frozen vegetables.
Erythorbic Acid is one of the popular food additives and ingredients in most countries, As a professional Erythorbic Acid supplier and manufacturer, Foodchem International Corporation has been supplying and exporting Erythorbic Acid from China for almost 10 years, please be assured to buy Erythorbic Acid at Foodchem. Any inquiries and problems please feel free to send emails to us via sales@foodchem.cn, we will reply you within 1 working day.

 

 

 

Erythorbic Acid
Language: 
Type:Antioxidants
CAS No:6381-77-7;7378-23-6
Qty in 20' FCL:22MT
Min. Order:3000KG
Packaging:Provide Neutral Packaging
D-Isoascorbic acid(Erythorbic acid) CAS 89-65-6
Erythorbic acid or erythorbate, formerly known as iso ascorbic acid and D-arabo ascorbic acid, is a stereoisomer of ascorbic acid. And its chemical properties have many similarities with Vc, but as an antioxidant, it has the inimitable advantage that Vc do not have: First, it is superior to the anti-oxidation than Vc
Introduction

 

Erythorbic acid or erythorbate, formerly known as iso ascorbic acid and D-arabo ascorbic acid, is a stereoisomer of ascorbic acid.

And its chemical properties have many similarities with Vc, but as an antioxidant, it has the inimitable advantage that Vc do not have: First, it is superior to the anti-oxidation than Vc, therefore, mixed the Vc, it can effectively protect the properties Vc component in improving the properties have very good results, while protecting the Vc color. Second, higher security, no residue in the human body, participating in metabolism after absorb by human body, which can be transformed into Vc partially. In recent years, Chinese medicine take it as complementary information be used in Vc film, Vc Yinqiao-Vc and health care products, and obtain good effect. Specification: 99%min Other name: D-erythro-Hexonicacid, 3-keto-, g-lactone(6CI);Erythorbic acid (7CI);Araboascorbic acid; Araboascorbic acid, D-;D-(-)-Isoascorbic acid;D-Araboascorbic acid;D-Erythorbic acid;D-Isoascorbicacid;D-arabino-Ascorbic acid;Glucosaccharonic acid;Isoascorbic acid;Isovitamin C;Saccharosonic acid

 

Functions and Applications

1.Erythorbic acid is produced in acidic condition by sodium erythorbate.

2.Erythorbic acid has strong reducing action and has effects on reducing blood press, diuresis,generationg liver glycogen,excreting pigment,detoxifying the body.

3.It is non-toxic.Its other applications are familiar to sodium erythorbate. Sodium erythorbateand erythorbic acid are generally recognized as the lastest A-class Green products internationally and have become the commodities in short supply both at home and abroad

 

 

 

 

Erythorbic acid.jpg
D-Isoascorbic acid
FCC, FG
Synonym: D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid, Glucosaccharonic acid, NSC 8117

 

 

 

CAS Number 89-65-6 Empirical Formula (Hill Notation) C6H8O6 Molecular Weight 176.12 FEMA Number 2410 Beilstein Registry Number 84271 EC Number 201-928-0 Council of Europe no. 30c MDL number MFCD00005378 PubChem Substance ID 24901050
D-Isoascorbic acid FCC, FG
SDS Specification Sheet (PDF)FTNMR (PDF) Similar Products
SKU-Pack Size Availability Price (EUR) 
W241008-SAMPLE-K

 

 

Estimated to ship on 09.08.19

36.80

W241008-1KG-K

 

 

Only 5 left in stock (more on the way) - FROM 
66.50

 

W241008-5KG-K

 

Estimated to ship on 05.09.19

187.00

 

 

To order products, please contact your local dealer. Click here
Product Recommendations

 

856061

D-(-)-Isoascorbic acid

98%

 

 


496332

 

Sodium D-isoascorbate monohydrate

97%

 

 


CDS024860

 

Sodium erythorbate

AldrichCPR

 

 

top
Purchase Safety & Documentation Protocols & Articles2 Peer-Reviewed Papers27 Related Products2
Properties
Related Categories A-D, Alphabetical Listings, Certified Food Grade Products, Flavors and Fragrances, H-J,
More...
biological source (Starch)
grade FG
Kosher
reg. compliance FCC
FDA 21 CFR (117)
FDA 21 CFR (175.105)
FDA 21 CFR (182.3041)
Show More (15) 
Description
Packaging
1 kg in poly bottle

 

5 kg in fiber drum

 

 

Other Notes
Download our Flavors and Fragrances Catalog to view our entire product line.

 

 

 

Subscribe to our Newsletter to keep up to date on our latest Flavors and Fragrances offerings.
erythorbic acid noun
er·?y·?thor·?bic acid | \ ?er-?-'th?r-bik- \
Definition of erythorbic acid
: a diastereoisomer of ascorbic acid with optical activity
First Known Use of erythorbic acid
1963, in the meaning defined above

 

 

 

History and Etymology for erythorbic acid
erythr- + ascorbic acid

 

 

 

Learn More about erythorbic acid
Share erythorbic acid
Post the Definition of erythorbic acid to Facebook Share the Definition of erythorbic acid on Twitter
Resources for erythorbic acid
Dictionary Entries near erythorbic acid
erythema migrans

 

erythematous

erythorbate

erythorbic acid

erythr-

erythraean

Erythraean

 

 

Statistics for erythorbic acid
Look-up Popularity

 

Bottom 10% of words

 

 

Time Traveler for erythorbic acid The first known use of erythorbic acid was in 1963
See more words from the same year

 

 

 

More Definitions for erythorbic acid
erythorbic acid noun
er·?y·?thor·?bic acid | \ ?er-?-'th?r-bik- \
Medical Definition of erythorbic acid
: a stereoisomer of vitamin C
Comments on erythorbic acid
What made you want to look up erythorbic acid? Please tell us where you read or heard it (including the quote, if possible).

 

 

 

Show Comments 
erythorbic acid[ er-uh-thawr-bik, er- ]SHOW IPA
WORD ORIGIN
noun Chemistry.
a crystalline compound, C6H8O6, soluble in water: used as an antioxidant for food and as a reducing agent in photography.
RELATED CONTENT
Y.E.S: These Words Are Acronyms
Read more in this article about some frequently asked questions and fun facts related to our definitions.
READ MORE
Famous Writers And Their Oddball Routines
Read more in this article about some frequently asked questions and fun facts related to our definitions.

 

 

 

Erythorbic acid
Molecular FormulaC6H8O6
Average mass176.124 Da
Monoisotopic mass176.032089 Da
ChemSpider ID16736142
defined stereocentres - 2 of 2 defined stereocentres

 

 

 

More details:
Featured data source
The Merck Index Online
This record has not been tagged.

 

 

 

TAG
Names
Properties
Searches
Spectra
Vendors
Articles
More 
Names and SynonymsDatabase ID(s)
Validated by Experts, Validated by Users, Non-Validated, Removed by Users
(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanon [German] [ACD/IUPAC Name]
(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone [ACD/IUPAC Name]
(5R)-5-[(1R)-1,2-Dihydroxyéthyl]-3,4-dihydroxy-2(5H)-furanone [French] [ACD/IUPAC Name]
(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
228-973-9 [EINECS]
2410
311332OII1
84271 [Beilstein]
89-65-6 [RN]
D-(-)-Isoascorbic acid
D-Araboascorbic Acid
D-erythro-3-Ketohexonic acid lactone
D-erythro-3-Oxohexonic acid lactone
D-erythro-Hex-2-enoic acid ?-lactone
D-erythro-Hex-2-enonic Acid g-Lactone
D-erythro-Hex-2-enonic acid, ?-lactone
D-Isoascorbic acid
Erycorbin
Erythorbic acid [Wiki]
Glucosaccharonic acid
KF3015000
Mercate "5"
Mercate 5
MFCD00005378 [MDL number]
Saccharosonic Acid
(2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
(5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-hydrofuran-2-one
(5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
(R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
[89-65-6]
2,3-Didehydro-D-erythro-hexono-1,4-lactone
6381-77-7 [RN]
Araboascorbic acid
D-(-)-Araboascorbic acid
D(-)-Isoascorbic acid
d(-)-isoascorbic acid 98%
d(-)-isoascorbic acid, 98%
d-(-)-isoascorbic acid, 98%
d-(-)-isoascorbicacid
D-ARABOASCORBICACID
D-Erythorbic acid
D-ERYTHRO-HEX-2-ENONIC ACID ?-LACTONE
D-erythro-hex-2-enono-1,4-lactone
D-Isoascorbic acid|D-Erythorbic acid
ISD
ISOASCORBIC ACID
Isovitamin C
UNII:311332OII1
UNII-311332OII1
Erythorbic Acid
Manufacturer: Confidential
Substance: Erythorbic Acid
CAS: 89-65-6
EC Number: 201-928-0
REACH: Not available
IUPAC Name: (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
GHS: Not available
Appearance: Solid
Molecular Formula: C6H8O6
Color: Not available
Molar Weight [g/mol]: 176.124
Concentration / Purity: 0.0%
Synonyms: Isoascorbic acid; D-Isoascorbic acid; D-Araboascorbic acid; Araboascorbic acid
Industries: Food & Feed
Product Groups: Antioxidants & Stabilizers
Required Documents: None
Other Restrictions: None
Other Certificates: None
Product ships to: To all countries.
Erythorbic acid (Isoascorbic acid) 315 or E315
Erythorbic acid, formerly known as isoascorbic acid and D-araboascorbic acid, is a stereoisomer of ascorbic acid (vitamin C); it is a vegetable-derived food additive produced from sucrose.

 

Be Awesome. Write a better description.

 

 

Type e.g. bulking agent, thickener, emulsifier, etc.
The function(s) performed by the food additive when used in cooking.

 

 

 

Antioxidant - Protects a food from deterioration caused by oxidation
Additive Variations one additive could be derived from a variety of sources/processes.
International Number Variant Name 
United States
European Union
Australia & New Zealand
315 / E315 N/A Erythorbic acid (Isoascorbic acid) 
Images e.g. chemical structure, molecular structure, origin, natural form, etc.
D Erythorbic Acid
Erythorbic Acid 3D Balls
Approvals and Bans i.e. not permitted in foods or safe to eat.
Data according to various sources such as fao, fda, codex. Spot a mistake? Tell us!

 

 

 

Country Status Matched Term
United States
Approved Erythorbic acid
European Union
Approved Erythorbic acid
Australia and New Zealand
Approved Erythorbic acid
show more

 

 

 

Diet and Health vegan, vegetarian, halal, genetically modified or genetically engineered, etc.
HALAL - YES
E315 - Erythorbic acid (Isoascorbic acid): Antioxidant.

 

Muslim Consumer Group

 

 

DERİVED FROM PLANT PRODUCTS - MAYBE
E315 - Erythorbic acid (Isoascorbic acid): Produced from sucrose. No know side effects. Other names: araboascorbic acid, d-isoascorbic acid, glucosaccharonic acid, erycorbin, saccharosonic acid

 

MBM Foods

 

 

Suggest research about this Additive
Synonyms i.e. alternative names
D-araboascorbic acid
Isoascorbic acid
Araboascorbic acid
D-araboascorbic acid
Dextro-araboascorbic acid
D-iso ascorbic acid
Dextro-iso ascorbic acid
Iso ascorbic acid 
Iso-ascorbic acid
2,3-didehydro-dextro-erythro-hexono-1,4-lactone
(2R)-2-[(1R)-1,2- dihydroxyethyl]-4,5-dihydroxyfuran-3-one
Erythorbic acid
D-erythorbic acid
Dextro-erythorbic acid
D-erythro-3-ketohexonic acid lactone
Dextro-erythro-3-ketohexonic acid lactone
D-erythro-3-oxohexonic acid lactone
Dextro-erythro-3-oxohexonic acid lactone
3-keto-D-erythro-hexonic acid gamma-lactone
3-keto-dextro-erythro-hexonic acid gamma-lactone
D-erythroascorbic acid
Dextro-erythroascorbic acid
Glucosaccharonic acid
Saccharosonic acid
Iso vitamin C

 

 

 

Sources e.g. fao, fda, wiki, wikipedia, codex, jecfa etc.
Collection of sources used to create this food additive summary.

 

 

 

Source
Codex Alimentarius 
Food Standards Australia New Zealand 
JECFA (Joint FAO/WHO Expert Committee on Food Additives) 
UK Food Guide 
UK Food Standards Agency 
U.S. Food and Drug Administration 
Wikipedia 
Key Identifiers i.e. Commonly used primary ids (keys) in other database or indexing schemas
Lists the U.S. CAS (Chemical Abstracts Service) registry number and EINECS (European INventory of Existing Commercial chemical Substances) numbers when known.

 

 

 

CAS Number: 89-65-6
EINECS Number: 201-928-0
Suppliers & Distributors for Erythorbic acid (Isoascorbic acid) - 315
No known suppliers. Get listed here - sales@noshly.com

 

 

 

Comments What do you think of this additive?
comments powered by Disqus
Erythorbic Acid
Company:
Jiangxi Dexing PARCHN Sodium Isovitamin C Co., Ltd.
DOCUMENTS
No additional documentation is available. Please visit the supplier's website to contact them for further information.

 

 

 

Join Prospector for free!
Prospector is a specialty search engine where you can:
Access 1000's of Technical Documents
Evaluate Material Data & Specifications
Get Pricing and Technical Assistance
CREATE YOUR FREE ACCOUNT

 

Jiangxi Dexing PARCHN Sodium Isovitamin C Co., Ltd. makes their documentation available in the regions indicated below:

 

 


Erythorbic Acid, is the stereo isomer of Vitamin C, chemical character is same as Vitamin C. Is white to light yellow white, crystal or crystal powder, odorless and is sour in taste. Used as an antioxidant of food, broadly used in meat food, fish food, beer, fruit juice, syrup crystal, fruit and vegetable, cake, dairy, produce, sherry, pickles, and grease.

 

 

 

COMPANY
Jiangxi top is one of the top ten food industries and has obtained recommended certification of quality food production and have implement the HACCP Plan and GMP standards. Their D-Erythorbic was recognized as a state level major new innovative product. Jiangxi is committed to continually achieve specializations and modern technologies .
Abstract
Erythorbic acid, a stereoisomer of ascorbic acid with similar physicochemical properties, is widely used as an antioxidant in processed foods. The aims of the present study were to evaluate the effect of erythorbic acid on iron absorption from ferrous sulfate at molar ratios of 2:1 and 4:1 (relative to iron) and to compare the effect of erythorbic acid directly with that of ascorbic acid at a molar ratio of 4:1. Iron absorption from iron-fortified cereal was measured in 10 women on the basis of erythrocyte incorporation of stable iron isotopes ((57)Fe or (58)Fe) 14 d after administration. Each woman consumed 4 ferrous-sulfate-fortified test meals (containing 5 mg Fe/meal) with or without added erythorbic or ascorbic acid. The data were evaluated by use of paired t tests, and the results are presented as geometric means. Iron absorption from the test meal without any added enhancer was 4.1%. The addition of erythorbic acid (at molar ratios of 2:1 and 4:1 relative to iron) increased iron absorption 2.6-fold (10.8%; P < 0.0001) and 4.6-fold (18.8%; P < 0.0001), respectively. The addition of ascorbic acid (molar ratio of 4:1) increased iron absorption 2.9-fold (11.7%; P = 0.0004). At a molar ratio of 4:1, erythorbic acid was 1.6-fold (P = 0.0002) as potent an enhancer of iron absorption as was ascorbic acid. Although erythorbic acid is a potent enhancer of iron absorption, its lack of antiscorbutic activity limits its usefulness in iron-fortification programs. However, it may play a major role in enhancing iron bioavailability from mixed diets that include foods preserved with erythorbic acid.
D-(-)-Isoascorbic acid
98%
Synonym: D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid, Glucosaccharonic acid, NSC 8117

 

 

 

CAS Number 89-65-6 Empirical Formula (Hill Notation) C6H8O6 Molecular Weight 176.12 Beilstein Registry Number 84271 EC Number 201-928-0 MDL number MFCD00005378 PubChem Substance ID 24888398
D-(-)-Isoascorbic acid 98%
SDS FTNMR (PDF) Similar Products
SKU-Pack Size Availability Price (EUR) 
856061-100G

 

 

 

Available to ship on 17.07.19 - FROM 
21.50

 

856061-500G

 

 

Available to ship on 17.07.19 - FROM 
44.80

 

 

 

To order products, please contact your local dealer. Click here
Product Recommendations

 

496332

Sodium D-isoascorbate monohydrate

97%

 

 


A92902

 

L-Ascorbic acid

99%

 

 


374385

 

D-Erythronic acid ?-lactone

95%

 

 

top
Purchase Safety & Documentation Peer-Reviewed Papers27
Properties
Related Categories Carbohydrate Chemistry, Carbohydrate Derivatives, Chemical Biology, Chemical Synthesis
InChI Key CIWBSHSKHKDKBQ-DUZGATOHSA-N
assay 98%
optical activity [?]25/D -16.8°, c = 2 in H2O
mp 169-172 °C (dec.) (lit.)
Description
Packaging
100, 500 g in poly bottle
Scientific Opinion on the re-evaluation of erythorbic acid (E 315) and sodium erythorbate (E 316) as food additives
food additive, erythorbic acid, E 315, CAS No 89-65-6, sodium erythorbate, E 316, CAS No 6381-77-7
First published in the EFSA Journal: 
20 January 2016
Adopted: 
9 December 2015
Type: 
Scientific Opinion
Abstract
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of erythorbic acid (E 315) and sodium erythorbate (E 316) as food additives. The use of these food additives was evaluated by the Scientific Committee on Food (SCF) that established an acceptable daily intake (ADI) of 6 mg/kg body weight (bw)/day. Intestinal absorption of erythorbate was reported from a mice study and near complete excretion within 24 h from a guinea pig study. The Panel noted that the acute toxicity of erythorbic acid or sodium erythorbate is low, there was no indication of adverse effects from the available subchronic toxicity studies, there is no concern with respect to their genotoxicity neither to respect to carcinogenicity. The Panel identified a no observed adverse effect level (NOAEL) of 650 mg/kg bw/day based on a decrease in body weight from a carcinogenicity study. No maternal and developmental effects were observed from a prenatal developmental toxicity study with sodium erythorbate. The Panel recognised the limitation of the overall toxicological database (no reproductive and chronic toxicity studies), but did not consider necessary to increase the usual uncertainty factor of 100 in deriving an ADI. Therefore, the Panel concluded that there is no reason to revise the current ADI of 6 mg/kg bw/day. Combined dietary exposure to erythorbic acid and sodium erythorbate from their use as food additives was calculated. Considering that the ADI is not exceeded by any population group, the Panel also concluded that the use of erythorbic acid (E 315) and sodium erythorbate (E 316) as food additives at the permitted or reported use and use levels would not be of safety concern.

 

 

 

© European Food Safety Authority, 2016
Panel members at the time of adoption
Fernando Aguilar, Riccardo Crebelli, Alessandro Di Domenico, Birgit Dusemund, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert-Remy, Claude Lambré, Jean-Charles Leblanc, Oliver Lindtner, Peter Moldeus, Alicja Mortensen, Pasquale Mosesso, Dominique Parent-Massin, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens-Berendsen, Rudolf Antonius Woutersen, Matthew Wright and Maged Younes.
Panel on Food Additives and Nutrient Sources Added to Food
Contact: fip@efsa.europa.eu DOI: 
10.2903/j.efsa.2016.4360
EFSA Journal 2016;14(1):4360
Question Number: EFSA-Q-2011-00482 EFSA-Q-2011-00483 On request from: 
European Commission
ERYTHORBIC ACID
Also known as: isoascorbic acid, D-araboascorbic acid,
Synonyms include: D-erythro-hexenonic acid, 3-keto, ?-lactone; D-isoascorbic acid; D-araboascorbic
acid; erycorbin; isovitamin C (SciFinder13, online).
Erythorbic acid is described in Commission Regulation (EU) No 231/201214, as a white to slightly
yellow crystalline solid, which darkens gradually on exposure to light. The substance has a melting
point of 164-172°C with decomposition. It is freely soluble in water and soluble in ethanol (JECFA,
2006). The measured Log Po/w value is -1.8515. Erythorbic acid is a diprotic acid having pKa's 11.34
and 4.04 (Naval Research Laboratory, 2000).
2.1.2. Sodium erythorbate (E 316)
The Panel noted that in the scientific literature different structural formulae of sodium erythorbate are
available. In some of the structural formulae, the exact position of the sodium cation is indicated; in
other formulae only the absolute configuration of the erythorbic acid moiety is given without an
indication of the exact position of the sodium ion in the molecule.
Sodium erythorbate (E 316) anhydrous has the molecular formula C6H7O6Na. The molecular weight is
198.11 g/mol. The CAS Registry Number is 6381-77-7, the EINECS number is 228-973-9 and the EC
name is 2,3-didehydro-3-O-sodio-D-erythro-hexono-1,4-lactone (EC Inventory, online). The
systematic name is D-erythro-hex-2-enonic acid, ?-lactone, sodium salt (1:1) (SciFinder, software).
Other names include: D-erythro-hex-2-enonic acid, ?-lactone, monosodium salt; araboascorbic acid,
monosodium salt; erythorbic acid sodium salt; sodium D-isoascorbate; sodium erythorbate (SciFinder,
software).
An isomeric form of sodium erythorbate anhydrous (C6H7O6?xNa) has the CAS registry No 7378-23-6,
the EC number 230-938-8 and the EC name isoascorbic acid, sodium salt. The systematic name is Derythro-hex-2-enonic acid, ?-lactone, sodium salt (1:X) (SciFinder, software). In this substance the
2.5. Reaction and fate in food
In aqueous solutions, the first degradation product of erythorbic acid is assumed to be
dehydroisoascorbic acid (Hvoslef and Petersen, 1981).
In the Pelletier (1969) study, the authors stated that:‘To test the theory that isoascorbic acid (IAA) was
retained by organs of animals, guinea pigs were fed a synthetic diet containing ascorbic acid (AA) plus
IAA. It was found that organs of the guinea pig retained a significant quantity of IAA which was
replaced a corresponding quantity of AA. The incorporated IAA could, in turn, be replaced by AA
when only AA was subsequently given in the diet.'
10. SCF (Scientific Committee for Food), 1995. Isoascorbic acid - monograph- Monograph
(Submitted by Prof, P.S. Elias, 8 January 1995 CS/ANT/23-Rev. 2. Submitted to EFSA from the
SCF's archive.
REFERENCES
Abe I, Saito S, Hori K, Suzuki M and Sato H, 1984. Sodium erythorbate is not carcinogenic in F344
rats. Experimental and Molecular Pathology, 41, 35-43
Aboul-Enein HY, Al-Duraibi IA, Raluca-Ioan S, Radoi C and Avramescu A, 1990. Analysis of L- and
D-ascorbic acid in fruits and "fruitdrinks by HPLC. Seminars in Food Analysis, 4, 31-37.
Andersen FA, 1999. Final report on the safety assessment of ascorbyl palmitate, ascorbyl dipalmitate,
ascorbyl stearate, erythorbic acid and sodium erythorbate. International Journal of Toxicology, 18,
1-26.
Baker EM, Tillotspm JA, Kennedy JE and Halver JE, 1973. Comparative metabolism of C14 labeled
ascorbic and isoascorbic acid. Federation Proceedings, Abstract, 4009, 665 (as referred to by SCF,
1997).
Barros AI, Silva AP, Gonçalves B and Nunes FM, 2010. A fast, simple, and reliable hydrophilic
interaction liquid chromatography method for the determination of ascorbic and isoascorbic acids.
Anal Bioanal Chem, 396, 1863-1875.
Bognár A and Daood HG, 2000. Simple in-line postcolumn oxidation and derivatization for the
simultaneous analysis of ascorbic and dehydroascorbic acids in foods. Journal of Chromatographic
Science, 38, 162-168.
Borenstein B, 1965. The comparative properties of isoascorbic acid and erythorbic acid. Food.
Technology, 19, 1719-1722.
Chen MJ, Chen HS, Lin CY and Chang HT, 1999. Indirect detection of organic acids in non-aqueous
capillary electrophoresis. Journal of Chromatography A, 853, 171-180.
Clairol, 1996. Mutagenicity of erythorbic acid. Correspondence from JF Corbett, dated June 14, 1996
(1 page) (as referred to by Andersen, 1999).
Davey MW, Bauw G and Montagu MV, 1996. Analysis of ascorbate in plant tissues by highperformance capillary zone electrophoresis. Analytical Biochemistry, 239, 8-19.
Drivelos S, Dasenaki ME and Thomaidis NS, 2010. Determination of isoascorbic acid in fish tissue by
hydrophilic interaction liquid chromatography-ultraviolet detection. Analytical and Bioanalytical
Chemistry, 397, 2199-2210.
EFSA (European Food Safety Authority), 2006. Scientific opinion of the Scientific Committee related
to uncertainties in dietary exposure assessment. EFSA Journal 2006;438, 54 pp.
doi:10.2903/j.efsa.2006.438
EFSA (European Food Safety Authority), 2010. Management of left-censored data in dietary exposure
assessment of chemical substances. EFSA Journal 2010;8(3):1557, 96 pp.
doi:10.2903/j.efsa.2010.1557 
Re-evaluation of E 315 and E 316 as food additives
EFSA Journal 2016;14(1):4360 34
EFSA (European Food Safety Authority), 2011a. Use of the EFSA Comprehensive European Food
Consumption Database in Exposure Assessment. EFSA Journal 2011;9(3):2097, 34 pp.
doi:10.2903/j.efsa.2011.2097
on the risk for public health related to the presence of mercury and methylmercury in food. EFSA
Journal 2012;10(12):2985, 241 pp. doi:10.2903/j.efsa.2012.2985
Ema M, Itami T and Kanoh S, 1985. Effect of sodium erythorbate on pregnant rats and their offpring.
Journal of Food Hygienic Society Japan, 26, 448-453.
Esselen WB, Powers JJ and Woodward R, 1945. D-Isoascorbic acid as an antioxidant. Industrial
Engineering and Chemistry, 37 (3), 295.
Fidler CF, Davidson L, Zeder C and Hurrell R, 2004. Erythorbic acid is a potent enhancer of
nonheme-iron absorption. The American Journal of Clinical Nutrition, 79, 99-102.
Fitzhugh OG and Nelson AA, 1946. Subacute and chronic toxicities of ascorbyl palmitates.
Proceedings of the Society for Experimental Biology and Medicine, 61, 195-198.
Fontannaz P, Kilinç T and Heudi O, 2006. HPLC-UV determination of total vitamin C in a wide range
of fortified food products. Food Chemistry, 94, 626-631.
Fukushima S, Kurata Y, Shibata MA, Ikawa E and Ito N, 1984. Promotion by ascorbyl acid, sodium
erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-
hydroxybutyl)nitrosamine. Cancer letters 23, 29-37.
Greger JL, Lee K, Graham KL, Chinn BL and Liebert JC, 1984. Iron, zinc and copper metabolism of
human subjects fed nitrite and erythorbate cured meats. Journal of Agricultural Food Chemistry,
32, 861-865.
Hayashi M, Kishi M, Sofuni T and Ishidate MJ, 1988. Micronucleus test in mice on 39 food additives
and eight miscellaneous chemicals. Food and Chemical Toxicology, 26, 487-500.
Hidiroglou N, Madere R and Behrens W, 1998. Electrochemical determination of ascorbic acid and
isoascorbic acid in ground meat and processed foods by high pressure liquid chromatography.
Journal of Food Composition and Analysis, 11, 89-96.
Hornig D, 1975. Distribution of ascorbic acid metabolites and analogues in man and animals. Annals
of the New York Academy of Sciences, 258, 103-118.
Hornig D and Weisser H, 1976. Interaction of erythorbic acid with ascorbic acid catabolism.
International Journal for Vitamin and Nutrition Research, 46, 40-47.
Hornig D, 1977. Interaction of erythorbic acid with ascorbic acid catabolism, 1977. Acta
vitaminologica et enzymologica, 31, 9-14. 
Re-evaluation of E 315 and E 316 as food additives
EFSA Journal 2016;14(1):4360 35
Hvoslef J and Petersen B, 1981. Structure of dehydroisoascorbic acid isomers in solution.
Carbohydrate Research, 92, 9-20.
Hughes RE and Hurley JE, 1969. The uptake of D-araboascorbic acid(D-isoascorbic acid) by guineapig tissues. British Journal of Nutrition, 23, 211-216.
Hughes RE and Jones PR, 1970. D-Araboascorbic acid and guine-pig scurvy. Nutrition report
international, 1, 275-279.
Inai K, Akamizu H, Eto R, Nishida T, Ohe K, Kobuke T, Nambu S, Matsuki K and Tokuoka S, 1989.
Tumorigenicity study of sodium erythrobate administered orally to mice. Hiroshima journal of
medical sciences, 38, 135-140.
Ishidate M Jr., Sofuni T, Yoshikawa K, Hayashi M, Nohmi T, Sawada M and Matsuoka A, 1984.
Primary mutagenicity screening of food additives currently used in Japan. Food Chemistry and
Toxicology, 22, 623-636.
JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1962. World health Organization.
Technical Report Series No. 228. Evaluation of the toxicity of a number of antimicrobials and
antioxidants. Sixth Report of the Joint FAO/WHO Expert Committee on Food Additives. Geneva,
Switzerland. Available online: http://apps.who.int/iris/bitstream/10665/40518/1/WHO_TRS_
228.pdf
JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1974. Toxicological evaluation of
some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers and
thickening agents. WHO Food Additive Series 5. World Health Organization. Geneva, Switzerland.
Available online: http://www.inchem.org/documents/jecfa/jecmono/v05je28.htm
JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1991. Erythorbic acid and its
sodium salt. First draft prepared by Dr R Walker. Available online:
http://www.inchem.org/documents/jecfa/jecmono/v28je03.htm
JECFA (Joint FAO/WHO Expert Committee on Food Additives), 2006. Monograph 1. Combined
compendium of food additive specifications. Available online: http://www.fao.org/ag/agn/jecfaadditives/search.html
Jorgenson TA, Rushbrook CJ, Newell GW and Green S, 1978. In vivo mutagenesis investigations of
four GRAS chemicals. Mutation Research 53, 205.
Kall MA and Andersen C, 1999. Improved method for simultaneous determination of ascorbic acid
and dehydroascorbic acid, isoascorbic acid and dehydroisoascorbic acid in food and biological
samples. Journal of Chromatography B, 730, 101-111.
Kawachi T, Komatsu T, Kada T, Ishidate M, Sasaki M, Sugiyama T and Tazima Y, 1980. Results of
recent studies on the relevance of various short-term screening tests in Japan. Applied Methods in
Oncology, 3, 253-267.
Klimisch HJ, Andreae M, Tillmann U, 1997. A systematic approach for evaluating the quality of
experimental toxicological and ecotoxicological data. Regulatory Toxicology and Pharmacology,
25, 1-5.
Lehman AJ, Fitzhugh OG, Nelson AA and Woodard G, 1951. The pharmacological evaluation of
antioxidants. Advances in Food Research, 3, 197-208.
Liao T, Wu JS, Wu MC and Chang HM, 2000. Epimeric separation of L-ascorbic acid and Disoascorbic acid by capillary zone electrophoresis. Journal of Agricultural and Food Chemistry, 48,
37-41.
Ling LB, Baeyens WR, Van Acker P and Dewaele C, 1992. Determination of ascorbic acid and
isoascorbic acid by capillary zone electrophoresis: application to fruit juices and to a
pharmaceutical formulation. Journal of Pharmaceutical and Biomedical Analysis, 10, 717-721. 
Re-evaluation of E 315 and E 316 as food additives
EFSA Journal 2016;14(1):4360 36
Madhavi DL, Singhal RS and Kulkarni PR, 1995. Food Antioxidants. Technological, toxicological
and health perspectives. Eds Madhavi DL, Despande SS and Salunkhe DK. Marcel Dekker Inc.
New York, 209-210.
Matsuoka A, Hayashi A and Ishidate JrM, 1979. Chromosomal aberration tests on 29 chemical
combined with S9 mix in vitro. Mutation Rearch, 66, 277-290.
Mellors AJ, Nahrwold DL and Rose RC, 1977. Ascorbic acid flux across mucosal border of guinea pig
and human ileum. American Journal of Physiology, 223, E374-E379.
Naval Research Laboratory, 2000. Cleaning method of VLF cooling water system development and
history of application with step-by-step procedure. Lamontagne RA. NRL/MR/6110-00-8471. 30
June, 2000.
Nonaka M, 1989. DNA repair tests on food additives. Environmental and Molecular Mutagenesis, 14
(Suppl. 15), 143.
OIV (International Organisation of Vine and Wine), 2008. Simultaneous determination of L-ascorbic
acid and D-iso-ascorbic acid (erythorbic acid) in wine by HPLC and UV-detection (Resolution
Oeno 11/2008) Method OIV-MA-AS313-22. Available online: http://www.oiv.int/oiv/files/6%20-
%20Domaines%20scientifiques/6%20-%204%20Methodes%20d%20analyses/6-4-1/EN/OIV-MAAS313-22.pdf
Pelletier O, 1969, Differential determination of D-isoascorbic acid and L-ascorbic acid in guinea pig
organs. Canadian Journal of Biochemistry, 47, 449-453.
Pelletier O, Godin C. 1969, Vitamin C activity of D-isoascorbic acid for the guinea pig. Canadian
Journal of Physiology and Pharmacology, 47, 985-991.
Peters JH et al., 1983. Effects of ascorbic and erythorbic acids on the Ames/Salmonella assay of
promutagens, mutagens and human urine concentrates. Modulation and mediation of cancer by
vitamins pp 104-133. Kager, Basel (as referred to by SCF, 1997).
Phillips AL, Mancini R, Sun Q, Lynch MP and Faustman C, 2001. Effect of erythorbic acid on cooked
color in ground beef. Meat Science, 57, 31-34.
Reyes P and Luh BS, 1962. Ascorbic and isoascorbic acids as antioxidants for frozen Freestone
peaches. Food Technology, 16, 116-118.
Water Solubility 1g/10mL
Merck 14,5126
BRN 84271
Stability:Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents.
InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N
CAS DataBase Reference89-65-6(CAS DataBase Reference)
EPA Substance Registry SystemD-erythro-Hex-2- enonic acid, .gamma.-lactone(89-65-6)
SAFETY
Risk and Safety StatementsHazard and Precautionary Statements (GHS)
Symbol(GHS): 
Signal word: Warning
Hazard statements: 
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning 
Precautionary statements: 
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Erythorbic Acid price More Price(10)
Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 856061 D-(?)-Isoascorbic acid 98% 89-65-6 100g $23.1 2018-11-13 Buy
Sigma-Aldrich 1241823 Erythorbic acid United States Pharmacopeia (USP) Reference Standard 89-65-6 50mg $386 2018-11-13 Buy
TCI Chemical A0520 D-Araboascorbic Acid >98.0%(T) 89-65-6 25g $14 2018-11-22 Buy
TCI Chemical A0520 D-Araboascorbic Acid >98.0%(T) 89-65-6 500g $48 2018-11-22 Buy
Alfa Aesar 036366 D-(-)-Isoascorbic acid, 99% 89-65-6 100g $26.4 2018-11-16 Buy
Erythorbic Acid Chemical Properties,Uses,Production
Chemical Properties
Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.
Uses
Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography.
Uses
Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150-200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.
Production Methods
Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.
Biotechnological Production
Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid.
Pharmaceutical Applications
Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.
Safety
Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid.
The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight.
storage
Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.
Purification Methods
Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]
Haihang Industry Co.,Ltd 86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8267 58
Hubei xin bonus chemical co. LTD 13657299721
zhangyuzhu@xhlchem.com CHINA 17424 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40275 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30168 84
View Lastest Price from Erythorbic Acid manufacturers
Image Release date Product Price Min. Order Purity Supply Ability Manufacturer 
2018-12-20 D-Isoascorbic acid
89-65-6 US $2.00 / kg 1kg 99% ask career henan chemical co
Erythorbic Acid Spectrum
D-Isoascorbic acid(89-65-6)1HNMRD-Isoascorbic acid(89-65-6)IR1D-Isoascorbic acid(89-65-6)MSD-Isoascorbic acid(89-65-6)IR2D-Isoascorbic acid(89-65-6)13CNMR
89-65-6(Erythorbic Acid)Related Search:
D-Isoascorbic acid Na salt,ISOASCORBIC ACID(RG),ISOASCORBIC ACID SODIUM SALT,Isoascorbic acid sodium,D(+)-ISOASCORBIC ACID SODIUM SALT,D-ISOASCORBIC ACID SODIUM SALT ?-Caprolactone Ascorbyl Palmitate ASCORBATE OXIDASE phosphoric acid 4-Hexanolide POLYCAPROLACTONE AVERAGE MN CA. 42 500 Sodium ascorbate trans-2-Hexenoic acid ISOASCORBIC ACID SODIUM SALT,D-ISOASCORBIC ACID SODIUM SALT,D(+)-ISOASCORBIC ACID SODIUM SALT Alginic Sodium Diester Glycine Citric acid Ascoric Acid Folic acid L-FUCOSE Ethyl 2-(Chlorosulfonyl)acetate L(+)-Ascorbic acid
Ascorbic Acid Impurity 6(Ascorbic Acid EP Impurity F)FEMA 2410ISOASCORBIC ACIDISOVITAMIN CD-(-)-ARABOASCORBIC ACIDD-ARABOASCORBIC ACIDD-ERYTHRO-3-KETOHEXANOIC ACIDLACTONED-ERYTHRO-3-OXOHEXANOIC ACID LACTONED-Erythro-hex-2-enonic acidD-ERYTHRO-HEX-2-ENONIC ACID, GAMMA-LACTONED-(-)-ERYTHORBIC ACIDD-ERYTHORBIC ACIDERYCORBINERYTHORBIC ACIDD(-)-ISOASCORBIC ACIDD-ISOASCORBIC ACID2,3-didehydro-d-erythro-hexono-1,4-lactoneSACCHAROSONIC ACIDNEOCEBICURE3-keto-d-erythro-hexonicacigamma-lactone araboascorbicacid d-arabino-ascorbicacid d-erythro-3-ketohexonicacidlactone D-Erythro-3-ketohex-onicacidlactone d-erythro-3-oxohexonicacidlactone d-erythro-ascorbicacid erythro-Hex-2-enonicacid,1,4-lactone femanumber:2410 glucosaccharonicacid mercate"5" mercate5 D-(-)-Isoascorbic acidD-erythro-Hex-2-enoic acid ?-lactoneD-ISOASCORBIC ACID 99+% FCCD-IsoascorbicAcid,>99%ERYTHORBICACID,FCCD-(-)-ARABOASCORBICACID(ERYTHORBICACID)Araboascorbic acid, D-D-erythro-Hex-2-enonic acid, ?-lactone (8CI, 9CI)D-erythro-Hexonic acid, 3-keto-, ?-lactone (6CI)D-erythro-Hex-2-enoic acid ?-lactone D-Araboascorbic acid D-Erythorbic Acid(2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-oneErythorbic acid (7CI)NSC 8117D-ASCORBICACIDERYTHORBATEErthorbic AcidD-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acidD-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid(R)-5-[(R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one3,4-Dihydroxy-5ß-[(R)-1,2-dihydroxyethyl]-2(5H)-furanoneD(-)-Isoascorbic acid,98%D-()-Isoascorbic acid,D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acidD-Isoascorbic acid,D-()-Isoascorbic acid, D-erythro-Hex-2-enoic acid ?-lactone, D-Araboascorbic acid, Erythorbic acid)-IsoascorD-(-Erythorbic Acid (50 mg)D-()-Isoascor
Copyright 2017 © ChemicalBook. All rights reserved

 

Synonyms: Erythorbic Acid; Eritorbik Asit; Erythorbicacid; Erythrobic acid; Erythorbic; Acid; D-(-)-Isoascorbic acid; D-erythro-Hex-2-enoic acid ?-lactone; D-Araboascorbic acid; Erythorbic acid; Glucosaccharonic acid; NSC 8117; Araboascorbic acid; D-; Isoascorbic Acid; Erythorbic acid; 89-65-6; D-Araboascorbic acid;

Acar Kimya A.Ş. © 2015 Tüm Hakları Saklıdır.