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ISO ASCORBIC ACID

ISO ASCORBIC ACID

SYNONYM: Erythorbic acid; ısoascorbıcacıd; isoascorbicacid; iso askorbic asit; ISOASCORBICACID; izoaskorbikasit; isoaskorbicasit; ERYTHORBIC ACID; Araboascorbic acid; Araboascorbic acid; Isoascorbicacid; Isoascorbic acid; Iso ascorbic acid; Iso-ascorbic acid; Iso vitamin C; izoascorbicacid; isoascorbicacit; isoaskorbicacid; isocorbicacid; ascorbicacid;iascorbicacid; iso ascorbic acid; iso ascorbic acid;iso ascorbic acid;ıso ascorbic acid;ıso ascorbıc acıd;iso askorbic acid;iso ascorbic asid; IZOASCORBICACID; ISOASCORBICASID; ISOASCORBICACIT; IZOASCORBICACID; isoaskorbic; İSO ASKORBİC ACİD; isoaskarbicasid; isoaskorbicasit; iso ascorbicacid

 

Molecular Formula:C6H8O6

 

Chemical Properties
Crystalline

 

 

Chemical Properties
Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.

 

 

Uses
Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography.

 

 

Uses
Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150-200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.

 

 

Production Methods
Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.

 

 

Biotechnological Production
Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid.

 

 

Pharmaceutical Applications
Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.

 

 

Safety
Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid.
The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight.

 

 

storage
Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.

 

 

Purification Methods
Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]

 

 

Incompatibilities
Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents.

 

 

Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).

 

Açıklaması

D-izoaskorbik asit, D-İzo askorbik asit olarak da adlandırılan Erythorbic Acid BP, EP, FCC, bir anti-oksidan olarak kullanılan askorbik asitin optik bir izomeridir.

 


Antioksidan olarak kullanılır. Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-izo askorbik asit), gıda maddelerinin ve oksijenin gıda üzerindeki etkilerini engelleyerek koruyucu madde olarak çalışan gıda katkı maddeleridir ve sağlığa yararlı olabilir. Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit), sadece orijinal gıda rengini ve doğal aromalarını korumakla kalmaz, aynı zamanda herhangi bir yan etkisi olmayan gıdaların raf ömrünü de arttırır.

 

Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit) gıda endüstrisinde önemli bir antioksidandır, gıdaların rengini, doğal lezzetini koruyabilir ve herhangi bir toksik ve yan etki olmadan depolama süresini uzatabilir. Erythorbic Acid BP, EP, FCC (D-isoascorbic acid, D-Iso askorbik asit), et işleme, meyve, sebze, teneke ve reçel vb. Alanlarda da kullanılır. Ayrıca bira, üzüm şarabı, yumuşak içecek gibi içeceklerde de kullanılır. içecek, meyve çayı ve meyve suyu vb.

 


Erythorbic asit (izoaskorbik asit, D-araboaskorbik asit, (D-) eritroaskorbik asit), askorbik asidin (C vitamini) bir stereoizomeridir. Metil 2-keto-D-glukonat ve sodyum metoksit arasındaki bir reaksiyon ile sentezlenir. Sükroz veya bu özellik için seçilmiş olan Penicillium suşları ile de sentezlenebilir. Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-İzo askorbik asit) E315 E ile gösterilir ve işlenmiş gıdalarda yaygın bir antioksidan olarak kullanılır.

 

Erithorbik asitin besin değeri yönlerini araştırmak için klinik denemeler yapılmıştır. Böyle bir çalışma, genç kadınlarda erythorbic asitin C vitamini metabolizması üzerindeki etkilerini araştırdı; C vitamini tutulumuna veya vücuttan temizlenmeye hiçbir etkisi bulunmamıştır. Daha sonraki bir araştırma, erithorbik asitin demir olmayan demir emiliminin güçlü bir güçlendiricisi olduğunu bulmuştur.

FDA, taze olarak tüketilmesi öngörülen yiyeceklerde (salata barları gibi) koruyucu olarak sülfit kullanımını yasakladığı için, Erythorbic Acid BP, EP, FCC (D-izoaskorbik asit, D-İzo askorbik asit) gıda koruyucu arttı.

Dahası, kürlenmiş etlerde ve dondurulmuş sebzelerde koruyucu olarak kullanılır.

 


Eskiden izoaskorbik asit ve D-araboaskorbik asit olarak bilinen eritrosit asit veya erithorbat, askorbik asitin bir stereoizomeridir. Sükrozdan üretilen bitkisel türevli bir besin katkısıdır. E Numara E315 ile gösterilir ve işlenmiş gıdalarda yaygın bir antioksidan olarak kullanılır. Erithorbik asitin besin değeri yönlerini araştırmak için klinik denemeler yapılmıştır. Böyle bir çalışma, genç kadınlarda erythorbic asitin C vitamini metabolizması üzerindeki etkilerini araştırdı; C vitamini tutulumuna veya vücuttan temizlenmeye hiçbir etkisi bulunmamıştır.

 

 


Ascorbyl Palmitate, Ascorbyl Dipalmitate and Ascorbyl Stearate are made from vitamin C (ascorbic acid). Erythorbic Acid and Sodium Erythorbate are substances with structures similar to vitamin C and the sodium salt of vitamin C. Ascorbyl Palmitate, Ascorbyl Dipalmitate and Ascorbyl Stearate are used primarily in makeup products. Erythorbic Acid and Sodium Erythorbate are used primarily in hair and nail products.

 

 


A comparison was made between the transfer of D-isoascorbic acid and L-ascorbic acid into the guinea pig eye. Saturation phenomena are demonstrated. A much higher plasma level is required for D-isoascorbic acid than for ascorbic acid in order to reach the saturation level in the aqueous humour. The affinity of ascorbic acid to the transport substrate is estimated to be 4-5 times higher than that of D-isoascorbic acid. The results are in agreement with the assumption that the transport mechanism is the same for the two substances.

 

 

Melting Point
169°C to 172°C (decomposition)

 

 

Product Categories
Food additives, flavours and adulterants, Neat reference materials, Food additives, flavours and adulterants

 

Molar Mass: 176.13 g/mol

Density: 0.704 g/cm3

soascorbic Acid (Vitamin C5), now called Erythorbic Acid, is an isomer of Ascorbic Acid (Vitamin C). Being an isomer of Ascorbic Acid, Isoascorbic Acid has the same kind and number of atoms as Vitamin C, but the atoms are arranged differently. Isoascorbic Acid (or Erythorbic Acid) has similar applications to Vitamin C as a water-soluble antioxidant. Used as a food additive in the United States, Isoascorbic Acid (or Erythorbic Acid) is readily used and metabolized in the body.

Being water-soluble and akin in molecular structure, Isoascorbic Acid (or Erythorbic Acid) is a close relative of Ascorbic Acid (Vitamin C). Ascorbic acid is chemically close to sugars and is renowned for its importance in the structure of connective tissue, collagen, bones, cartilage, teeth, gums, and eyes. Ascorbic acid is essential in the repair and production of cells.

Ascorbic acid and is 6 stable esters have been shown to lower cholesterol, strengthen the immune system, and reduce the signs of aging. There are 6 stable esters of vitamin C, all of which prove useful in the body in the different ways they are absorbed. These include: Vitamin C1-Ascorbic Acid, VItamin C2-Dehyroascorbic Acid, Vitamin C3-Ascorbyl Palmitate, VItamin C4-Calcium Ascorbate, Vitamin C5-Isoascorbic Acid, Vitamin C6-Calcium Isoascorbate, and lastly, Ascorbign, or provitamin C (the direct precursor of ascorbic acid) is also useful and appears to potentiate, if not accelerate, vitamin C activity.

Erythorbic acid is readily absorbed and metabolized. Following an oral dose of 500 mg of erythorbic acid to human subjects the blood level curves for ascorbic acid and erythorbic acid showed a similar rise. In five human subjects, an oral dose of 300 mg was shown to have no effect on urinary excretion of ascorbic acid (Kadin & Osadca, 1959). Erythorbic acid was found to have no antagonistic effect on the action of ascorbic acid (Gould, 1948).

 

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